Research Studies

Protocol Number Status
COVID-19 and Substance Misuse Case Identification using Data Science: A Retrospective Cohort Study CTN-0111 Development
Randomized, Placebo-controlled Trial of Injectable Naltrexone and Monthly Injectable Buprenorphine for Methamphetamine Use Disorder (MURB) CTN-0110 Development
Randomized, Placebo-controlled Trial of Injectable Naltrexone and Monthly Injectable Buprenorphine for Cocaine Use Disorder (CURB-2) CTN-0109 Development
Transcranial Magnetic Stimulation for the Treatment of Methamphetamine/Cocaine Use Disorder CTN-0108 Development
Peer recovery Support: A Bridge to Treatment for Overdose Survivors (NIH HEAL Initiative) CTN-0107 Development
Derivation and Validation of New Measurement-Based Care Tools Derived from the Brief Addiction Monitor (NIH HEAL Initiative) CTN-0106 Development
Integrating pharmacy-based prevention and treatment of opioid and other substance use disorders: A survey of pharmacists and stakeholder (NIH HEAL Initiative) CTN-0105 Development
Healthcare Provider Stigma Related to the Opioid Use Epidemic and its Impact on Patient Treatment and Clinical Management CTN-0104 Development
Expanding Clinical Research Training on Implementing the Evidence-based Hub and Spoke Model of Medication-Assisted Treatment for Opioid Use Disorder (NIH HEAL Initiative) CTN-0103 Active
Rural Expansion of Medication Treatment for Opioid Use Disorder (NIH HEAL Initiative) CTN-0102 Development
Subthreshold Opioid Use Disorder Prevention (STOP) Trial (NIH HEAL Initiative) CTN-0101 Development
Optimizing Retention, Duration, and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (NIH HEAL Initiative) CTN-0100 Development
Emergency Department-INitiated bupreNOrphine and VAlidaTIOn Network Trial (ED-INNOVATION) (NIH HEAL Initiative) CTN-0099 Active
Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE) (NIH HEAL Initiative) CTN-0098 Development
Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone (SWIFT): Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (NIH HEAL Initiative) CTN-0097 Development
Culturally Centered MAT for OUD Implementation Facilitation for Primary Care and Addiction Treatment Programs Serving American Indian/Alaska Natives (NIH HEAL Initiative) CTN-0096 Active
Clinic-Randomized Trial of Clinical Decision Support for Opioid Use Disorders in Medical Settings (NIH HEAL Initiative) CTN-0095 Development
Individual Level Predictive Modeling of Opioid Use Disorder Treatment Outcome (NIH HEAL Initiative) CTN-0094 Active
Validation of a Community Pharmacy-based Prescription Drug Monitoring Program Risk Screening Tool (PHARMSCREEN) (NIH HEAL Initiative) CTN-0093 Active
Preventing and Identifying Opioid Use Disorder using the Six Building Blocks (6BBs) for Improving Opioid Prescription Management (NIH HEAL Initiative) CTN-0091 Completed
Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution (NIH HEAL Initiative) CTN-0090 Active
Integrating Nurse Practitioner Buprenorphine Waiver Training into Graduate Nursing Curriculum (NIH HEAL Initiative) CTN-0089 Completed
DC Research Infrastructure Building & Initiative to Reach, Engage, and Retain in MAT patients with OUD (NIH HEAL Initiative) CTN-0088 Active
A Foundation to Examine Reasons for Discontinuation for Buprenorphine Care in the Veterans Health Administration (NIH HEAL Initiative) CTN-0087 Completed
Inpatient versus Outpatient Treatment Outcomes for People with Opioid Use Disorder (NIH HEAL Initiative) CTN-0086 Completed
Selection Bias-Free Estimation of the Impact of Drug-Focused 12-step Mutual Help Groups (NIH HEAL Initiative) CTN-0085 Completed
Developing a Prescription Opioid Registry across Diverse Health Systems (NIH HEAL Initiative) CTN-0084 Active
Using Social Media to Deliver HIV Self-Testing Kits and Link to Online PrEP Services CTN-0083 Active
Implementation Survey of PrEP and Opioid Use Related Services in STI Clinics and MSM-Centered Community Based Organizations (CBOs) CTN-0082 Development
Emergency Medicine Opioid Data Infrastructure: Key Venue to Address Opioid Morbidity and Mortality (Project CODE PRO – Capturing Opioid Use Disorder Electronically and Patient Reported Outcomes) CTN-0081 Development
Medication Treatment for Opioid-dependent Expecting Mothers (MOMs): A Pragmatic Randomized Trial Comparing Two Buprenorphine Formulations CTN-0080 Active
Emergency Department Connection to Care with Buprenorphine for Opioid Use Disorder (ED-CONNECT) CTN-0079 Completed
Knowledge of and Attitudes about Medication Assisted Treatment within American Indian Communities CTN-0078 Active
Medical Cannabis Use among Primary Care Patients: Using Electronic Health Records to Study Large Populations CTN-0077 Completed
Clinical decision support for Opioid use disorders in Medical settings: Pilot Usability Testing in an EMR (COMPUTE) CTN-0076 Completed
Pharmacy Screening and Collaborative Opioid Use Disorder Care (Pharm-OUD-Care) CTN-0075 Completed
Primary Care Opioid Use Disorders Treatment Trial Economic Analysis Study (NIH HEAL Initiative) CTN-0074-A-1 Active
Primary Care Opioid Use Disorders Treatment Trial CTN-0074 Active
Towards Detecting Cocaine Use Using Smartwatches in the NIDA Clinical Trials Network CTN-0073 Completed
Patient and System-Level Factors Associated with HEDIS AOD-IET Measure Performance across Health Systems CTN-0072 Completed
Electronic Health Records Data Elements Research (EHR-DARE) CTN-0071 Completed
Interpretation and Implementation of Title 42 CFR Part 2 for Confidentiality of Patient Drug and Alcohol Use Records: NIDA CTN Stakeholder Snapshot CTN-0070 Completed
Opioid Use Disorder in the Emergency Department CTN-0069 Active
Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder CTN-0068 Completed
Comparing Treatments for HIV-Positive Opioid Users in an Integrated Care Effectiveness Study (CHOICES); Scale-Up CTN-0067 Completed
Opioid Use Disorders in Primary Care Settings: Linking EHRs with PDMP and National Death Index Data Systems CTN-0066 Completed
Evaluation of Drug Screening Implementation in Primary Care CTN-0065 Completed
Linkage to Hepatitis C Virus Care among HIV/HCV Co-infected Substance Users CTN-0064 Completed
Gender Differences in the Interrelationships between Sexual Abuse, Risky Sexual Behavior, and Anxiety/Depression in Treatment Efficacy and Drug Use over Time among Individuals with Substance Use Disorders CTN-0063 Completed
A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements into the Electronic Health Record in Large Primary Care Settings CTN-0062 Active