En español

Government Shutdown

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at USA.gov.

Research Studies

Protocol Number Status
Knowledge of and Attitudes about Medication Assisted Treatment within American Indian Communities CTN-0078 Development
Medical Cannabis Use among Primary Care Patients: Using Electronic Health Records to Study Large Populations CTN-0077 Development
Clinical decision support for Opioid use disorders in Medical settings: Pilot Usability Testing in an EMR (COMPUTE) CTN-0076 Development
Pharmacy Screening and Collaborative Opioid Use Disorder Care (Pharm-OUD-Care) CTN-0075 Development
Primary Care Opioid Use Disorders Treatment Trial CTN-0074 Development
Towards Detecting Cocaine Use Using Smartwatches in the NIDA Clinical Trials Network CTN-0073 Active
Patient and System-Level Factors Associated with HEDIS AOD-IET Measure Performance across Health Systems CTN-0072 Completed
Electronic Health Records Data Elements Research (EHR-DARE) CTN-0071 Completed
Interpretation and Implementation of Title 42 CFR Part 2 for Confidentiality of Patient Drug and Alcohol Use Records: NIDA CTN Stakeholder Snapshot CTN-0070 Completed
Opioid Use Disorder in the Emergency Department CTN-0069 Active
Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder CTN-0068 Active
Comparing Treatments for HIV-Positive Opioid Users in an Integrated Care Effectiveness Study (CHOICES); Scale-Up CTN-0067 Development
Opioid Use Disorders in Primary Care Settings: Linking EHRs with PDMP and National Death Index Data Systems CTN-0066 Completed
Evaluation of Drug Screening Implementation in Primary Care CTN-0065 Completed
Linkage to Hepatitis C Virus Care among HIV/HCV Co-infected Substance Users CTN-0064 Active
Gender Differences in the Interrelationships between Sexual Abuse, Risky Sexual Behavior, and Anxiety/Depression in Treatment Efficacy and Drug Use over Time among Individuals with Substance Use Disorders CTN-0063 Completed
A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements into the Electronic Health Record in Large Primary Care Settings CTN-0062 Active
Kaiser Virtual Data Warehouse - Prescription Opioid Users CTN-0061 Completed
Tobacco, Alcohol, Prescription Medications, and Substance Use/Misuse Brief screen/assessment tool (TAPS Tool) CTN-0059 Completed
Screening, Brief Intervention, and Referral to Treatment in Primary Care (SBIRT-PC): An add-on project to “Duke University CMS Innovation Award Southeastern Diabetes Initiative” CTN-0057 Completed
Testing and Linkage to HIV Care in China: a Cluster Randomized Trial CTN-0056 Completed
Comparing Treatments for HIV-Positive Opioid Users in an Integrated Care Effectiveness Study (CHOICES) CTN-0055 Completed
Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT) CTN-0054 Completed
Achieving Cannabis Cessation: Evaluating N-Acetylcysteine Treatment (ACCENT) CTN-0053 Completed
A Randomized Controlled Evaluation of Buspirone for Relapse-Prevention in Adults with Cocaine Dependence (BRAC) CTN-0052 Completed
Extended-Release Naltrexone vs. Buprenorphine for Opioid Treatment (X:BOT) CTN-0051 Completed
The START Follow-Up Study CTN-0050 Completed
Project HOPE: Hospital Visit as Opportunity for Prevention and Engagement for HIV-Infected Drug Users CTN-0049 Completed
Cocaine Use Reduction with Buprenorphine (CURB) CTN-0048 Completed
Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED) CTN-0047 Completed
Smoking-Cessation and Stimulant Treatment (S-CAST): Evaluation of the Impact of Concurrent Outpatient Smoking-Cessation and Stimulant Treatment on Stimulant-Dependence Outcomes CTN-0046 Completed
Web-delivery of Evidence-Based, Psychosocial Treatment for Substance Use Disorders CTN-0044 Completed
Stimulant Reduction Intervention using Dosed Exercise CTN-0037 Completed
HIV Rapid Testing and Counseling in Drug Abuse Treatment Programs in the U.S. CTN-0032 Completed
An Evaluation of Neurocognitive Function, Oxidative Damage, and their Association with Treatment Outcomes in Methamphetamine and Cocaine Abusers CTN-0031-A-1 Completed
Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): Evaluation of a Combined Individual-Group Intervention to Reduce Stimulant and Other Drug Use by Increasing 12-Step Involvement CTN-0031 Completed
Prescription Opioid Addiction Treatment Study (POATS) CTN-0030 Completed
A Pilot Study of Osmotic-Release Methylphenidate (OROS-MPH) in Initiating and Maintaining Abstinence in Smokers with Attention Deficit Hyperactivity Disorder (ADHD) CTN-0029 Completed
Randomized Controlled Trial of Osmotic-Release Methylphenidate (OROS-MPH) for Attention Deficit Hyperactivity Disorder in Adolescents with Substance Use Disorders CTN-0028 Completed
Starting Treatment with Agonist Replacement Therapies (START) Study CTN-0027 Completed
Motivational Enhancement Treatment to Improve Treatment Engagement and Outcome for Spanish-Speaking Individuals Seeking Treatment for Substance Abuse CTN-0021 Completed
Job-Seekers Training for Patients with Drug Dependence CTN-0020 Completed
Reducing HIV/STD Risk Behaviors: A Research Study for Women in Drug Abuse Treatment CTN-0019 Completed
Reducing HIV/STD Risk Behaviors: A Research Study for Men in Drug Abuse Treatment CTN-0018 Completed
HIV and HCV Intervention in Drug Treatment Settings CTN-0017 Completed
Patient Feedback: A Performance Improvement Study in Outpatient Addiction Treatment CTN-0016 Completed
Women's Treatment for Trauma and Substance Use Disorders CTN-0015 Completed
Brief Strategic Family Therapy (BSFT) for Adolescent Drug Abusers CTN-0014 Completed
Motivational Enhancement Therapy to Improve Treatment Utilization and Outcome in Pregnant Substance Users CTN-0013 Completed
Characteristics of Screening, Evaluation, and Treatment of HIV/AIDS, Hepatitis C Viral Infection, and Sexually Transmitted Infections in Substance Abuse Treatment Programs CTN-0012 Completed
A Feasibility Study of a Telephone Enhancement Procedure (TELE) To Improve Participation in Continuing Care Activities CTN-0011 Completed
Buprenorphine/Naloxone (Bup/Nx) Facilitated Rehabilitation for Heroin Addicted Adolescents/Young Adults CTN-0010 Completed
Smoking Cessation Treatment with Transdermal Nicotine Replacement Therapy in Substance Abuse Rehabilitation Programs CTN-0009 Completed
A Baseline for Investigating Diffusion of Innovation CTN-0008 Completed
Motivational Incentives for Enhanced Drug Abuse Recovery: Methadone Clinics CTN-0007 Completed
Motivational Incentives for Enhanced Drug Abuse Recovery: Drug Free Clinics CTN-0006 Completed
Motivational Interviewing (MI) To Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse CTN-0005 Completed
MET (Motivational Enhancement Treatment) To Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse CTN-0004 Completed
Suboxone® (Buprenorphine/Naloxone) Taper: A Comparison of Two Schedules CTN-0003 Completed
Buprenorphine/Naloxone (Bup/Nx) versus Clonidine for Outpatient Opiate Detoxification CTN-0002 Completed
Buprenorphine/Naloxone (Bup/Nx) versus Clonidine for Inpatient Opiate Detoxification CTN-0001 Completed

Blending Initiative

blending logo

Formed with SAMHSA to reduce the gap between research results and treatment.