Research Studies

Protocol	Number	Status
Examining the COVID-19 Public Health Emergency on Policy, Substance Use Disorder, Treatment and Resilience among American Indian and Alaska Native Communities	CTN-0118	Development
The Impact of COVID-19 Pandemic on Substance Use Treatment Services	CTN-0117	Development
Pharmacist-Integrated Model of Medication Treatment for Opioid Use Disorder	CTN-0116	Development
Developing an Intervention to Address Intersecting Prescription Opioid and Chronic Pain Stigma in Cancer Survivors (NIH HEAL Initiative)	CTN-0115	Development
Drug Repurposing for Cocaine Use Disorder (CUD) Using a Combined Strategy of Artificial Intelligence (AI)-Based Prediction and Retrospective Clinical Corroboration	CTN-0114	Development
Validating a DSM-5 Substance Use Disorder (SUD) Symptom Checklist in EHR Data from a Large Primary Care Sample to Support Future Pragmatic Trials and Chronic Care Management of SUDs in Primary Care	CTN-0113	Development
Optimal Policies to Improve Methadone Maintenance Adherence Longterm (OPTIMMAL)	CTN-0112	Development
COVID-19 and Substance Misuse Case Identification using Data Science: A Retrospective Cohort Study	CTN-0111	Development
Randomized, Double-Blind, Placebo-Controlled Trial of Monthly Injectable Buprenorphine for Methamphetamine Use Disorder (MURB)	CTN-0110	Development
Randomized, Placebo-Controlled Trial of Injectable Naltrexone and Monthly Injectable Buprenorphine for Cocaine Use Disorder (CURB-2)	CTN-0109	Development
Transcranial Magnetic Stimulation for the Treatment of Methamphetamine/Cocaine Use Disorder	CTN-0108	Development
Peer recovery Support: A Bridge to Treatment for Overdose Survivors (NIH HEAL Initiative)	CTN-0107	Development
Derivation and Validation of New Measurement-Based Care Tools Derived from the Brief Addiction Monitor (NIH HEAL Initiative)	CTN-0106	Active
Integrating pharmacy-based prevention and treatment of opioid and other substance use disorders: A survey of pharmacists and stakeholder (NIH HEAL Initiative)	CTN-0105	Development
Healthcare Provider Stigma Related to the Opioid Use Epidemic and its Impact on Patient Treatment and Clinical Management	CTN-0104	Active
Expanding Clinical Research Training on Implementing the Evidence-based Hub and Spoke Model of Medication-Assisted Treatment for Opioid Use Disorder (NIH HEAL Initiative)	CTN-0103	Completed
Rural Expansion of Medication Treatment for Opioid Use Disorder (NIH HEAL Initiative)	CTN-0102	Active
Subthreshold Opioid Use Disorder Prevention (STOP) Trial (NIH HEAL Initiative)	CTN-0101	Active
Optimizing Retention, Duration, and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (NIH HEAL Initiative)	CTN-0100	Development
Emergency Department-INitiated bupreNOrphine and VAlidaTIOn Network Trial (ED-INNOVATION) (NIH HEAL Initiative)	CTN-0099	Active
Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE) (NIH HEAL Initiative)	CTN-0098	Development
Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone (SWIFT): Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (NIH HEAL Initiative)	CTN-0097	Development
Culturally Centered MAT for OUD Implementation Facilitation for Primary Care and Addiction Treatment Programs Serving American Indian/Alaska Natives (NIH HEAL Initiative)	CTN-0096	Active
Reducing Stigma Toward People with Opioid Use Disorder Among Primary Care Clinicians (NIH HEAL Initiative)	CTN-0095-A-2	Development
Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder (NIH HEAL Initiative)	CTN-0095-A-1	Development
Clinic-Randomized Trial of Clinical Decision Support for Opioid Use Disorders in Medical Settings (NIH HEAL Initiative)	CTN-0095	Active
Individual Level Predictive Modeling of Opioid Use Disorder Treatment Outcome (NIH HEAL Initiative)	CTN-0094	Active
Validation of a Community Pharmacy-based Prescription Drug Monitoring Program Risk Screening Tool (PHARMSCREEN) (NIH HEAL Initiative)	CTN-0093	Completed
Preventing and Identifying Opioid Use Disorder using the Six Building Blocks (6BBs) for Improving Opioid Prescription Management (NIH HEAL Initiative)	CTN-0091	Completed
Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution (NIH HEAL Initiative)	CTN-0090	Completed
Integrating Nurse Practitioner Buprenorphine Waiver Training into Graduate Nursing Curriculum (NIH HEAL Initiative)	CTN-0089	Completed
DC Research Infrastructure Building & Initiative to Reach, Engage, and Retain in MAT patients with OUD (NIH HEAL Initiative)	CTN-0088	Active
A Foundation to Examine Reasons for Discontinuation for Buprenorphine Care in the Veterans Health Administration (NIH HEAL Initiative)	CTN-0087	Completed
Inpatient versus Outpatient Treatment Outcomes for People with Opioid Use Disorder (NIH HEAL Initiative)	CTN-0086	Completed
Selection Bias-Free Estimation of the Impact of Drug-Focused 12-step Mutual Help Groups (NIH HEAL Initiative)	CTN-0085	Completed
Developing a Prescription Opioid Registry across Diverse Health Systems (NIH HEAL Initiative)	CTN-0084	Active
Using Social Media to Deliver HIV Self-Testing Kits and Link to Online PrEP Services	CTN-0083	Completed
Implementation Survey of PrEP and Opioid Use Related Services in STI Clinics and MSM-Centered Community Based Organizations (CBOs)	CTN-0082	Active
Emergency Medicine Opioid Data Infrastructure: Key Venue to Address Opioid Morbidity and Mortality (Project CODE PRO – Capturing Opioid Use Disorder Electronically and Patient Reported Outcomes)	CTN-0081	Completed
Medication Treatment for Opioid-dependent Expecting Mothers (MOMs): A Pragmatic Randomized Trial Comparing Two Buprenorphine Formulations	CTN-0080	Active
Emergency Department Connection to Care with Buprenorphine for Opioid Use Disorder (ED-CONNECT)	CTN-0079	Completed
Knowledge of and Attitudes about Medication Assisted Treatment within American Indian Communities	CTN-0078	Active
Medical Cannabis Use among Primary Care Patients: Using Electronic Health Records to Study Large Populations	CTN-0077	Completed
Clinical decision support for Opioid use disorders in Medical settings: Pilot Usability Testing in an EMR (COMPUTE)	CTN-0076	Completed
Pharmacy Screening and Collaborative Opioid Use Disorder Care (Pharm-OUD-Care)	CTN-0075	Completed
Primary Care Opioid Use Disorders Treatment Trial Economic Analysis Study (NIH HEAL Initiative)	CTN-0074-A-1	Active
Primary Care Opioid Use Disorders Treatment Trial	CTN-0074	Active
Towards Detecting Cocaine Use Using Smartwatches in the NIDA Clinical Trials Network	CTN-0073	Completed
Patient and System-Level Factors Associated with HEDIS AOD-IET Measure Performance across Health Systems	CTN-0072	Completed
Electronic Health Records Data Elements Research (EHR-DARE)	CTN-0071	Completed
Interpretation and Implementation of Title 42 CFR Part 2 for Confidentiality of Patient Drug and Alcohol Use Records: NIDA CTN Stakeholder Snapshot	CTN-0070	Completed
Opioid Use Disorder in the Emergency Department	CTN-0069	Completed
Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder	CTN-0068	Completed
Comparing Treatments for HIV-Positive Opioid Users in an Integrated Care Effectiveness Study (CHOICES); Scale-Up	CTN-0067	Completed
Opioid Use Disorders in Primary Care Settings: Linking EHRs with PDMP and National Death Index Data Systems	CTN-0066	Completed
Evaluation of Drug Screening Implementation in Primary Care	CTN-0065	Completed
Linkage to Hepatitis C Virus Care among HIV/HCV Co-infected Substance Users	CTN-0064	Completed
Gender Differences in the Interrelationships between Sexual Abuse, Risky Sexual Behavior, and Anxiety/Depression in Treatment Efficacy and Drug Use over Time among Individuals with Substance Use Disorders	CTN-0063	Completed
A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements into the Electronic Health Record in Large Primary Care Settings	CTN-0062	Completed