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Primary Care Opioid Use Disorders Treatment Trial Economic Analysis Study (NIH HEAL Initiative)

Funded by the NIH HEAL Initiative

Effective treatment for OUD has been shown to improve patient outcomes, and reduce healthcare costs; however, evidence of this effect in primary care settings is severely limited. The health economic findings from this study will supplement the parent PROUD trial’s results regarding clinical effectiveness and implementation outcomes and provide critical contextual information for health systems and other healthcare stakeholders. The study will evaluate the economic viability of the PROUD collaborative care model for OUD; that is, from the perspective of the healthcare sector, to what extent do the downstream cost savings associated with improved patient outcomes offset the additional costs of the PROUD intervention. The specific aims are to: 1) estimate the start-up and ongoing management costs of the PROUD intervention; 2) assess costs associated with healthcare utilization for patients who receive primary care treatment in PROUD and usual care clinics, and have been identified with recognized OUDs prior to clinic randomization; 3) estimate the economic value of the PROUD intervention, measured as net monetary benefit (NMB, incremental benefit – incremental cost), from the healthcare sector perspective.

CTN Protocol ID: 
Principal Investigator(s)
Katharine Bradley, M.D., M.P.H.
Senior Investigator
Group Health Research Institute
Metropolitan Park East
1730 Minor Avenue, Ste. 1600
Seattle, WA 98101

Sean Murphy, Ph.D.
Associate Professor of Research
Weill Cornell Medicine
Health Policy and Research
425 East 61st Street, Suite 301
New York, NY 10065

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