En español

MDMA (Ecstasy) Abuse

Is MDMA Addictive?

MDMA affects many of the same neurotransmitter systems in the brain that are targeted by other addictive drugs. Experiments have shown that animals will self administer MDMA—an important indicator of a drug’s dependency potential—although the degree of self-administration is less than some other drugs of abuse such as cocaine.34

image of students in classroom setting

Few studies have attempted to assess MDMA dependency among users in the general population, and those that have been conducted have shown widely varying results, likely because of the different population samples and different types of measures used. We do know that some MDMA users report symptoms including: continued use despite knowledge of physical or psychological harm; tolerance (or diminished response); and withdrawal effects, such as fatigue, loss of appetite, depressed feelings, and trouble concentrating.

This page was last updated March 2006

Get this Publication

Cite this article

NIDA. (2006, March 1). MDMA (Ecstasy) Abuse. Retrieved from https://www.drugabuse.gov/publications/research-reports/mdma-ecstasy-abuse

press ctrl+c to copy
NIDA Notes: The Latest in Drug Abuse Research

​Research Reports

This series of reports simplifies the science of research findings for the educated lay public, legislators, educational groups, and practitioners. The series reports on research findings of national interest.

Lesson Plan and Activity Finder