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Treatment

As Opioid Use Disorders Increased, Prescriptions for Treatment Did Not Keep Pace

Several effective medications are now available for treating opioid use disorder but many patients who could benefit do not receive them. Some patients who receive the medications face challenges to staying in treatment.

Treatment

Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

A clinical trial found that patients who self-administered cognitive behavioral therapy (CBT) using computerized training modules reduced their drug use as much as patients who received clinician-delivered CBT, and they maintained this advantage through a 6-month follow-up.

Treatment

In Animals, Opioid Combination Shows Promise for Safer Pain Relief

In rats, the combination treatment of oxycodone/nalfurafine had lower levels of abuse liability and produced less respiratory depression than oxycodone alone.

Treatment

Novel Compound Alleviates Hard-to-Treat Pain in Mice

A novel compound called GAT211 alleviates inflammatory and neuropathic pain in mice without producing tolerance or signs of abuse liability.

Treatment

Cigarette Smoking Increases the Likelihood of Drug Use Relapse

Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

Narrative of Discovery

Narrative of Discovery: The Quest for a Medication to Treat Methamphetamine Addiction, Part 3

Dr. Linda Dwoskin feels just one small step away from success in her effort to develop the first ever medication to treat methamphetamine addiction.

Treatment

After Showing Promise for Cannabis-Using Adolescents, N-Acetylcysteine Falters in Adult Study

In a clinical trial, N-acetylcysteine did not help adults reduce their cannabis use, despite having been effective for adolescents in a previous trial. The results indicated that if adults are able to benefit from the medication, they will likely require a different treatment regimen than adolescents.

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