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Your search for Brain and Addiction returned 8 results. Search again.

Basic Science

Machine Learning Applied to Brain Imaging Data Predicts Response to Cocaine Use Disorder Treatment

This study demonstrated that functional connectivity among a large number of brain regions predicts patients’ chances of achieving abstinence in treatment for cocaine use disorder.

Basic Science

THC Exposure in Adolescence Disrupts Brain Maturation in Animals

Exposing adolescent rats to THC disrupted normal maturation of a key set of neurons in a brain area that corresponds to the human prefrontal cortex. The disruptions produced structural differences that resemble patterns which have been observed in people with addiction and schizophrenia.

Basic Science

El consumo de marihuana en la adolescencia está vinculado a alteraciones en el circuito neural y en los síntomas del estado de ánimo

Un estudio encontró que el consumo de marihuana en la adolescencia está vinculado a alteraciones en el circuito neural.

Basic Science

Research Links Adolescent Substance Use to Adult Brain Volumes

This research revealed associations between nicotine, alcohol, and marijuana use during two periods of adolescence and smaller gray matter volume in two brain areas at age 25.

Basic Science

Transcription Factor E2F3a Mediates Cocaine’s Effects on Gene Expression and Addiction-Related Behaviors

This study demonstrated that cocaine increases expression of the protein E2F3a in the brain’s reward system. The changes in E2F3a levels in the nucleus accumbens are tied to addiction-related behaviors and to altered gene expression.

Basic Science

Cocaine-Induced Increase in an Immune Protein Promotes Addiction Behaviors in Mice

Cocaine produces a portion of its rewarding effects by increasing levels of granulocyte-colony stimulating factor (G-CSF) in the brain’s reward center. Treatments that prevent G-CSF signaling in the nucleus accumbens might reduce motivation to use cocaine.

Basic Science

Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22.

Treatment

Deep Brain Stimulation Attenuates Rats’ Responses to Heroin

High-frequency electrical stimulation of neurons deep in the brain can reduce rats’ relapse-like behavior and motivation to take heroin. The finding strengthens hope that deep brain stimulation might offer a new treatment alternative for opioid addiction, particularly for patients who have not benefited from other treatments.

NIDA Notes

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