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Your search for Marijuana returned 17 results. Search again.

Basic Science

Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22.

Basic Science

Why Marijuana Displeases

This study demonstrated how THC produces aversive effects in mice and suggests a mechanism to explain why people experience rewarding, aversive, or mixed effects from marijuana.

Public Health

Long-Term Marijuana Use Is Associated With Health Problems Later in Life

Researchers used the statistical technique of latent class analysis to describe distinct patterns of marijuana use across age using data from nearly 10,000 participants in the Monitoring the Future study. Longer-term marijuana use (extending from age 18 into the late 20s or beyond) was associated with increased risk of self-reported health problems at age 50.

Treatment

After Showing Promise for Cannabis-Using Adolescents, N-Acetylcysteine Falters in Adult Study

In a clinical trial, N-acetylcysteine did not help adults reduce their cannabis use, despite having been effective for adolescents in a previous trial. The results indicated that if adults are able to benefit from the medication, they will likely require a different treatment regimen than adolescents.

Basic Science

Regular Marijuana Use Is Associated With Differences in Brain Gray Matter and Connectivity

A brain imaging study strongly suggests that regular users of marijuana have smaller orbitofrontal cortex (OFC) volumes. Such a deficit could make it more difficult to change counterproductive behaviors, including drug use.

Public Health

Study Questions Role for Marijuana in Teen Users’ IQ Decline

In a recent study, teens who used marijuana lost IQ points relative to their nonusing peers. However, the drug appeared not to be the culprit.

Public Health

Study Links Medical Marijuana Dispensaries to Reduced Mortality From Opioid Overdose

Legally protected marijuana dispensaries (LMDs) were associated with lower rates of dependence on prescription opioids, and deaths due to opioid overdose, than would have been expected based on prior trends. However, LMDs also were associated with higher rates of recreational marijuana use and increased potency of illegal marijuana.

Basic Science

THC Hampers Spatial Memory Development in Young Monkeys

Adolescent monkeys that were exposed to THC fell progressively further behind THC-free monkeys in their ability to recall the location of an object after a brief delay.

Basic Science

Animal Study Suggests Marijuana May Affect Future Offspring’s Susceptibility to Heroin

Can marijuana use put offspring at heightened risk for opiate addiction, even if the use stops before the offspring are conceived? Results from a recent NIDA-funded study are consistent with other studies suggesting that a parent’s history of drug use, even preconception, may affect a child’s brain function and behavior.

Treatment

Dr. Kevin M. Gray Q & A: A Potential Medication for Marijuana Dependence

Dr. Kevin M. Gray discusses why it’s the perfect time for discovering new evidence-based treatments for marijuana dependence. In an accompanying podcast, he discusses a clinical trial that examines NAC’s potential as a treatment for marijuana dependence among adults.

Public Health

Self-Control Protects Urban Minority Youths From Drug Use and Depressive Mood

Interventions that bolster self-control in childhood and early adolescence might shield ethnic and racial minority adolescents and young adults from the burden of both drug use and depressive mood.

Public Health

Among High School Seniors, Driving After Marijuana Use Surpasses Drunk Driving

Within the 2 weeks prior to responding to a nationwide survey, 28 percent of high school seniors were in a vehicle whose driver had been using marijuana or another illicit drug, or had drunk 5 or more alcoholic drinks.

Basic Science

Device Detects Marijuana in Breath Hours After Smoking

Driving under the influence of marijuana is a dangerous public health concern. NIDA researchers have discovered that breath expelled into a Breathalyzer-style collection device contained measurable amounts of THC for up to 2 hours after participants in a recent clinical trial smoked the drug.

Basic Science

Marijuana Use May Promote Nicotine Consumption

Exposing rats to THC increases the likelihood that the animals will later self-administer nicotine. THC-exposed rats are also willing to work harder to obtain nicotine. When extrapolated to people, the findings suggest that THC’s pharmacological impact on the brain may make a person who uses marijuana more vulnerable to developing nicotine addiction, an underappreciated health consequence of marijuana use.

Public Health

In Nationwide Survey, More Students Use Marijuana, Fewer Use Other Drugs

Almost one-third (32 percent) of the roughly 42,000 Monitoring the Future survey respondents reported having used marijuana during their lifetime. However, abuse of many other drugs—methamphetamine, heroin, cocaine, and some prescription medications—declined.

Prevention

Intervention Strengthens American Indian Teen Mothers’ Parenting

Teen mothers on three American Indian reservations improved on several measures of parenting after participating in Family Spirit, a home-visiting intervention developed with NIDA support. At 12 months postpartum, the women’s children exhibited reduced rates of emotional difficulties predicting later drug abuse and other behavioral problems. Infants at highest risk—those whose mothers had histories of drug abuse—benefited the most.

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