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Treatment

Switching to Reduced-Nicotine Cigarettes May Aid in Quitting Smoking

Smokers who switch to cigarettes with very low nicotine content may experience mild and transient increases in some withdrawal symptoms. Cigarettes with reduced nicotine will be easier to quit than the cigarettes marketed at present.

Public Health

E-Cigarettes Promote Smoking Progression in Youth and Depress Quitting Among Adults

E-cigarettes are not an effective tool to reduce combustible-cigarette smoking, two NIDA-supported studies indicate.

Treatment

Cigarette Smoking Increases the Likelihood of Drug Use Relapse

Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

Treatment

Varenicline Helps People With Mental Illness Maintain Abstinence From Smoking

The finding from an 18-month-long clinical trial strengthens hope that pharmacotherapy can break nicotine’s especially tenacious hold on people with serious mental illness such as bipolar disorder or schizophrenia.

Public Health

Smoking Cessation Does Not Interfere With Recovery From Substance Use

Despite common concerns that encouraging patients to quit smoking might endanger their success in treatment of substance use and mood or anxiety disorders, smoking cessation appears unlikely to hinder and may even help recovery.

Basic Science

A Genetic Nexus of Obesity and Smoking

Research shows that some gene variants that influence body mass index also shape smoking behaviors.

NIDA @ Work

Dr. Joni Rutter Q&A: How Basic Science Is Tackling Addiction

One of NIDA’s goals is to try to understand the individual differences that contribute to whether or not someone who takes a drug will become addicted to it. Dr. Rutter’s research focuses on three types of differences: Environmental, developmental, and genetic and epigenetic.

Basic Science

Marijuana Use May Promote Nicotine Consumption

Exposing rats to THC increases the likelihood that the animals will later self-administer nicotine. THC-exposed rats are also willing to work harder to obtain nicotine. When extrapolated to people, the findings suggest that THC’s pharmacological impact on the brain may make a person who uses marijuana more vulnerable to developing nicotine addiction, an underappreciated health consequence of marijuana use.

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