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Complex brain actions reflect multiple networks of activity in the brain, according to a paper authored by researchers from the NIDA Intramural Research Program, in collaboration with scientists from Italy...
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A new animal study from NIDA's Intramural Research Program (IRP) shines light on the underlying mechanisms in the brain's prefrontal cortex and its role in learning.
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A recent study published in Lancet found that extended-release naltrexone was equally effective at reducing illicit opioid use as the partial agonist buprenorphine if patients could be successfully initiated on...
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This study found that: Marijuana users exhibited six different patterns of marijuana use from ages 18 to 50. Longer-term marijuana use (extending from age 18 into the late 20s or...
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Scientists at the National Institute on Drug Abuse’s Intramural Research Program (NIDA IRP) have demonstrated distinct roles for two subregions of the orbitofrontal cortex (OFC) in goal-directed behaviors.
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This study: Showed that stressful life events are associated with reductions in a person’s chances of becoming or remaining abstinent from drugs for at least 3 years. Suggests that coping...
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Nicotine-containing electronic cigarettes (e-cigs) produce brain changes similar to those caused by other nicotine sources, such as combustible cigarettes or nicotine lozenges, a study sponsored by the National Institute on...
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The authors of this study assessed whether the Washington state hospital mandates had any impact on Medicaid beneficiary opioid dispensing rates after an ED visit.
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This study found that: Childhood poverty was associated with reduced volumes of limbic brain regions in adulthood. The reduced limbic volumes were associated with depression and smoking in adulthood. Participation...
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NIDA and NJOY, LLC, have developed a Standard Research E-Cigarette. The device will help researchers resolve many outstanding questions about how e-cigarettes affect health.
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2017 brought exciting new basic science findings, including some striking new insights into the structure and functioning of receptors that play important roles in substance use, addiction, and pain.
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Researchers supported by the National Institute on Drug Abuse have developed a protocol for adjunctive oxytocin treatment, and a pilot study has indicated that it is workable and safe for...
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Today the results of the 2017 Monitoring the Future (MTF) survey were released by NIDA-funded researchers at the University of Michigan at Ann Arbor, and overall the news is encouraging.
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NIH-funded science continues to make great strides in the fight against HIV. To foster such research, 10 years ago NIDA created its Avant-Garde Award competition to fund bold projects that...
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This research: Demonstrated that use of anabolic-androgenic steroids (AAS) is associated with compromised heart pumping and atherosclerotic plaque. Suggests that clinicians should inquire about AAS use when young or middle-aged...
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Social media and crowdsourcing apps could be particularly useful for gathering and sharing information in real time about overdoses and using that information to prevent overdose deaths, thereby translating “citizen...
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Scientists supported by the National Institute on Drug Abuse conducted a proof-of-concept study examining the potential efficacy of a cannabinoid receptor (CB1) partial agonist, dronabinol, in relieving signs and symptoms...
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This study demonstrated that the new axons arrive via a pathway that originates in the VTA and passes through the part of the forebrain called the nucleus accumbens (NAC).
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When we speak of addiction as a chronic disorder of the brain, it thus includes an understanding that some individuals are more susceptible to drug use and addiction than others.
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This study: Showed strong associations between substance use disorder diagnoses and 19 major medical illnesses among patients in a large, integrated health care system. Indicates that these associations may persist...
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A team from the University of Minnesota, Twin Cities, and Auburn University in Auburn, Alabama, examined the effects of childhood ADHD symptoms on the development of smoking in male and...
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This research: Showed that high-frequency electrical stimulation of neurons deep in the brain can reduce rats’ relapse-like behavior and motivation to take heroin. Strengthens hope that deep brain stimulation might...
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In a recent study supported by the National Institute on Drug Abuse, cognitive behavioral therapy (CBT) and contingency management (CM) increased brain efficiency in regions that coordinate cognitive control—the ability...
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Investigators at the National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) have identified a resting-state brain circuit whose functional connectivity predicts the likelihood of relapse to cocaine use.
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Researchers found that: N-acetylcysteine did not help adults reduce their cannabis use, despite having been effective for adolescents in a previous trial. If adults are able to benefit from the...