Opioid Dose Variability Associated with Overdose
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A new study funded by the National Institute on Drug Abuse found that high dose variability increases the odds for an opioid overdose independent of dose alone.
News Releases
Opioids without the risk of addiction?
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Investigators have found that the opioid-galanin receptor heteromers determine the different effects of methadone as compared to morphine and fentanyl, showing methadone with a weaker ability to activate the dopaminergic...
Dr. Jack Stein appointed NIDA Chief of Staff
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Dr. Nora Volkow, Director of the National Institute on Drug Abuse (NIDA), has appointed Jack B. Stein, Ph.D., to be the NIDA Chief of Staff, a newly created position to...
Opioid Overdose Reversal News: FDA-approved naloxone devices produce substantially higher blood levels of naloxone than improvised nasal spray
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A new study looked at how well the FDA-approved nasal spray and autoinjector compared to the improvised nasal devices, which are not FDA-approved.
Serotonin Unexpectedly Regulates Expression of Brain Genes
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The brain chemical serotonin can regulate expression of genes within neurons in a very unexpected way, as described in a NIDA-funded paper just published in the journal Nature.
New toolkit for genomic editing holds promise for addiction research
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The scientific world has advanced immeasurably by the science of DNA and genetics. Manipulating gene expression to change the way that cells such as neurons function has helped scientists create...
Monthly buprenorphine injections effective for opioid use disorders
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A newly published study suggests the long-acting buprenorphine formulation BUP-XR is more effective than placebo in helping patients struggling with addiction to opioids. BUP-XR is a monthly extended-release injection.
Higher rates of NAS linked with economic conditions
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A NIDA-funded analysis of eight states showed a significant association between rates of neonatal abstinence syndrome (NAS) and poor economic conditions.
Cascade of Care model recommended for opioid crisis
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A team of NIDA-funded scientists has offered a critical look at how to build an improved framework of care for the identification and treatment of people with opioid use disorder...
A whole new view of CB2
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NIDA-funded scientists have recently identified the crystal structure of the CB1 receptor and have some understanding of how it modulates the system.
Scientists closer to finding inherited traits in addiction
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Scientists have concluded that the risk of addiction is a complex combination of both genes and environmental influences.
Teens using vaping devices in record numbers
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America’s teens report a dramatic increase in their use of vaping devices in just a single year, with 37.3 percent of 12th graders reporting “any vaping” in the past 12...
National Institute on Drug Abuse to hold teleconference discussing key findings of 2018 Monitoring the Future Survey on teen drug use
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The National Institute on Drug Abuse (NIDA) will hold a teleconference on Monday, December 17, to discuss the results of the 2018 Monitoring the Future (MTF) survey.
ABCD study completes enrollment, announces opportunities for scientific engagement
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The National Institutes of Health announced today that enrollment for the Adolescent Brain Cognitive Development (ABCD) Study is now complete and, in early 2019, scientists will have access to baseline...
Registration opens for 2019 National Drugs & Alcohol Chat Day
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Registration is now open for the 12th annual National Drugs & Alcohol Chat Day, a live web chat between high school teenagers and addiction and mental health scientists.
NIDA-NIAAA 2018 Mini-Convention: Frontiers in Addiction Research
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The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), both part of the National Institutes of Health, will host a one-day mini...
Study shows impact of social interactions on addictive behavior
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A new study published in Nature Neuroscience finds that social interactions can have a profound effect on behaviors related to addiction, and on the brain’s response to drug-associated cues.
New opioid treatment resources for emergency department clinicians
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The National Institute on Drug Abuse (NIDA) today announced the availability of informational resources for clinicians interested in initiating buprenorphine treatment in emergency department settings.
Daily use of marijuana among non-college young adults at all time high
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The National Institute on Drug Abuse (NIDA) announced that the latest Monitoring the Future (MTF) survey results on substance use trends as teens transition to adulthood are now available online...
Event registration opens today for National Drug & Alcohol Facts Week®
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The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) announced today that event registration is open for the next National Drug &...
Journal commentary addresses role of dentists in opioid crisis
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The commentary, authored by Dr. Nora Volkow, director of the National Institute on Drug Abuse, and Dr. Martha Somerman, director of the National Institute of Dental and Craniofacial Research, both...
Study casts doubt on effectiveness of e-cigs for smoking cessation
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A study found no evidence that smokers who used e-cigarettes and other electronic nicotine delivery systems (ENDS) in the United States were more likely to quit smoking cigarettes than smokers...
2018 Avenir award recipient to study how social networks affect people who use drugs
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A proposal to study how drug users who are part of social networks influence their own communities has been given the 2018 Avenir award for HIV/AIDS research by the National...
New clinician screening tool available for substance use
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The National Institute on Drug Abuse (NIDA) Clinical Trials Network has unveiled a new scientifically validated, online screening tool designed to assess a patient’s risk for substance misuse and substance...
Training module now available for acute pain management in hospitalized adults
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A case-based clinician training module designed for the evaluation of acute pain and opioid management for adults is now available through the Centers of Excellence in Pain Education (CoEPE) program...
Analysis of insurance coverage for back pain shows missed opportunities to prescribe non-opioid medications
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A comprehensive analysis of health insurance coverage of non-opioid and opioid medications to treat chronic low back pain concluded that some insurance plans have missed important opportunities to steer patients...
Methadone and buprenorphine reduce risk of death after opioid overdose
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A National Institutes of Health-funded study found that treatment of opioid use disorder with either methadone or buprenorphine following a nonfatal opioid overdose is associated with significant reductions in opioid...
Special journal issue highlights ABCD brain study
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The special issue is an overview of the ABCD Study and includes articles about the rationale for the study, its design and recruitment strategy, assessment protocols and neuroimaging parameters, the...
Full survey of annual teen drug use now available with additional data
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The complete volume of the 2017 Monitoring the Future Survey (MTF) teen drug use and behavior survey results is now available online with never before seen highlights about drug use...
Higher rate of substance use among Native American youth on reservations
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A survey comparing drug use among Native American youth living on or near reservations to a national sample of American youth found that Native American youth report substantially higher use...