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Tissue and Cell Repositories

Revised November 2015

  • Handbook of Human Tissue Sources: A National Resource of Human Tissue Samples Molecular Databases
    Science and Technology Policy Institute at RAND.report on human tissue repositories, commissioned by the National Bioethics Advisory Commission (NBAC), represent the first inventory of stored tissue sample repositories in the United States.
  • National Institute on Drug Abuse Center for Genetic Studies
    The National Institute on Drug Abuse (NIDA) ( www.drugabuse.gov/), in collaboration with The NIH (http://www.nih.gov ), has established the Center for Genetic Studies, under a contract to Rutgers University and its subcontractor, Washington University, to produce, store, and distribute clinical data and biomaterials (DNA samples and cell lines) available in the NIDA Genetics Initiative.
  • COGA: The Collaborative Study on the Genetics of Alcoholism
    The Collaborative Study on the Genetics of Alcoholism (COGA) is a multi-site, multi-disciplinary undertaking with the overall goals of characterizing the familial transmission of alcoholism and related phenotypes and identifying susceptibility genes using genetic linkage.
  • NIGMS Human Genetic Cell Repository
    By providing the resources for human genome research, the HUMAN GENETIC CELL REPOSITORY , sponsored by the National Institute of General Medical Sciences (NIGMS), supplies scientists with the materials for accelerating disease gene discovery. The resources available include highly-characterized, viable, and contaminant-free cell cultures and high quality, well-characterized DNA samples derived from these cultures, both subjected to rigorous quality control.
  • Coriell Cell Repositories provide essential research reagents to the scientific community by establishing, verifying, maintaining, and distributing cells cultures and DNA derived from cell cultures. These collections, supported by funds from the National Institutes of Health (NIH) and several foundations, are extensively utilized by research scientists around the world.
  • NIA Cell Repository
    Sponsored by the National Institute on Aging (NIA), the AGING CELL REPOSITORY , is a resource facilitating cellular and molecular research studies on the mechanisms of aging and the degenerative processes associated with it.
  • NINDS Human Genetics Resource Center at the Coriell Institute is a growing bank for human cells, DNA samples, clinical data, and information sources, to accelerate research on genetics of disorders of the nervous system.
  • The Autism Research Resource at The Coriell Institute for Medical Research
    The State of New Jersey funded the initiation of a genetic resource to support the study of autism in families where more than one child is affected or where one child is affected and one demonstrates another significant and related developmental disorder. This resource now receives continuing support from the Coriell Institute for Medical Research. An open bank of anonymously collected materials documented by a detailed clinical diagnosis forms the basis of this growing database of information about the disease. The Autism Resource is housed at the Coriell Institute for Medical Research in New Jersey , which holds the world's largest collection of human cells for use in genetic research and where much of the standard technology of culturing, storing, and distributing cells has been developed.
  • The National Pathology Repository, located at the Joint Pathology Center, accessions and stores material coded by pathologic diagnosis. The National Repository currently stores over 2.8 million cases accessioned and coded since 1917. The material comprises written records and over 50 million microscopic slides, 30 million paraffin tissue blocks, and 12 million preserved wet tissue specimens. Annually, approximately 60,000 new cases are accessioned and coded into the National Repository. Cases represent both sexes, all races/ethnicities, all ages, and come from contributors worldwide. These cases represent the entire spectrum of human and animal disease.
  • Department of Defense DNA Registry
    To provide worldwide scientific consultation, research, and education services in the field of forensic DNA analysis to the Department of Defense (DoD) and other agencies. To provide DNA reference specimen collection, accession, and storage of United States military and other authorized personnel.
  • P3G - Public Population Project in Genomics.
    Four different but complementary population genomics research projects involving whole populations -- Quebec 's CARTaGENE, GenomEUtwin project (involving 8 countries), Estonia 's genome project and the U.K. Biobank -- decided to come together and create an international consortium: Public Population Project in Genomics (P3G).
  • The Alzheimer's Disease Consortium
    The AD consortium is a collaborative effort to develop a shared clinical and genotype database for the study of late-onset Alzheimer's Disease.
  • National Donor Marrow Program Laboratory and Repositories
    The National Marrow Donor Program (NMDP) laboratories and repositories play an essential role in the process of matching donors with patients in need of a stem cell transplant. Three DNA Repositories store blood samples from potential donors listed on the Registry. Five contract laboratories perform histocompatibility testing to determine the donor's tissue type.
  • The HGDP CEPH diversity Panel
    A resource of 1064 cultured lymphoblastoid cell lines (LCLs) from individuals in 51 different world populations and corresponding milligram quantities of DNA is banked at the Foundation Jean Dausset (CEPH) in Paris.
  • Harvard Brain Tissue Resource Center, McLean Hospital
    The Harvard Brain Tissue Resource Center has been established at McLean Hospital as a centralized resource for the collection and distribution of human brain specimens for brain research.
  • Stanley Brain Research Laboratory and Brain Collection
    Begun in 1994, the Stanley Brain Collection makes postmortem brain tissue from individuals with schizophrenia, bipolar disorder, major depression, and normal controls available to researchers without charge. The specimens are collected with the assistance of participating medical examiners. Permission of the next-of-kin is obtained in all cases.
  • The NHLBI Biologic Specimen Repository
    Since the mid-1970s, the Institute's Blood Division has established and supported several large blood specimen repositories to perform prospective and retrospective studies of blood donors and recipients. Use of these samples has been extensive, and from 1991-1998, a total of 54,336 specimens from the NHLBI Biological Specimen Repository were sent to various investigators.
  • NHLBI Limited Access Data Sets
    Data sets generated with NHLBI support that are available to qualified scientific investigators.
  • Framingham Heart Study
    The objective of the Framingham Heart Study was to identify the common factors or characteristics that contribute to cardiovascular disease (CVD) by following its development over a long period of time in a large group of participants who had not yet developed overt symptoms of CVD or suffered a heart attack or stroke. Genetic material and data are available to qualified scientific researchers.
  • NCI Cooperative Tissue Network
    The Cooperative Human Tissue Network (CHTN) specializes in the prospective procurement, preservation and distribution of human tissues for research. In addition to normal, benign and malignant tissues, tissues from patients with specific diseases such as ulcerative colitis, a premalignant state, are provided.

This page was last updated November 2015