Synthetic Cannabinoids (K2/Spice)

synthetic drug "spice" in a plastic bag
Photo by © Shutterstock/gaikova

Synthetic cannabinoids are human-made mind-altering chemicals that are either sprayed on dried, shredded plant material so they can be smoked or sold as liquids to be vaporized and inhaled in e-cigarettes and other devices. These products are also known as herbal or liquid incense. Learn about the health effects of synthetic cannabinoids and read the DrugFacts.

Common Names

K2, Spice, Joker, Black Mamba, Kush, and Kronic

3.3% of high school seniors used synthetic cannabinoids in the past year.

Source: 2019 Monitoring the Future Survey

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Clinical trials are research studies in human volunteers conducted to answer specific health questions. Learn about the NIH-sponsored clinical trials available to you.