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The Neurobiology of Drug Addiction

9: Brain regions mediating the development of morphine dependence

Brain regions mediating the development of morphine dependence

The development of dependence to morphine also involves specific areas of the brain, separate from the reward pathway.  In this case, point to the thalamus and the brainstem (green dots).  The parts of the reward pathway involved in heroin (morphine) addiction are shown for comparison.  Many of the withdrawal symptoms from heroin or morphine are generated when the opioid receptors in the thalamus and brainstem are deprived of the drug.

This page was last updated November 2019

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NIDA. (2019, November 19). The Neurobiology of Drug Addiction. Retrieved from https://www.drugabuse.gov/neurobiology-drug-addiction

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