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NIDA Notes

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers (October 2009)

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Manic Mice Show Heightened Sensitivity to Rewards (October 2009)

Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction (April 2009)

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Prenatal Nicotine Exposure May Damage Receptors That Influence Auditory Processing (April 2009)

Reports on a series of animal experiments indicating that nicotine exposure during prenatal fetal development damages a set of receptors in the brain's auditory processing center.

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Cocaine Locks Rats Into Unrewarding Behaviors (April 2009)

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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High School Seniors Report Alcohol- or Drug-Impaired Driving Experiences (April 2009)

Examines the incidence of high school seniors’ alcohol- or drug-related driving experiences based on 2001 through 2006 data.

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Methamphetamine Abusers Show Increased Distractibility (April 2009)

Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.

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NIDA's National Advisory Council Welcomes New Members (April 2009)

Introduces five new members to the NIDA National Advisory Council meeting, including Drs. Xavier Castellanos, Steven Childers, Thomas Crowley, Anita Everett, and Hazel Szeto.

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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment (April 2009)

Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

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Damage to Brain Area May Immediately Halt Cigarette Addiction (April 2009)

Describes a study among people who had sustained brain injuries to investigate whether certain damaged areas of the brain are associated with the ability to quit smoking.

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