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NIDA Notes Articles: All

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Long-Term Follow-Up of Medication-Assisted Treatment for Addiction to Pain Relievers Yields “Cause for Optimism”

November 2015

In the first long-term follow-up of patients treated with buprenorphine/naloxone for addiction to opioid pain relievers, half reported that they were abstinent from the drugs 18 months after starting the therapy.

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Digital Addiction Therapies Affirm Promise in Replication and Large Trial

November 2015

Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.

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Childhood Maltreatment Changes Cortical Network Architecture and May Raise Risk for Substance Use

November 2015

Young adults who had been maltreated as children differed from others who had not been maltreated in the connectivity of nine cortical regions. The differences could compromise the maltreated group’s basic social perceptual skills, ability to maintain a healthy balance between introversion and extroversion, and ability to self-regulate their emotions and behavior.

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Narrative of Discovery: Can Magnets Treat Cocaine Addiction?

September 2015

Two researchers share their reasons for researching transcranial magnetic stimulation (TMS) for treating cocaine addiction, and describe challenges to moving forward this potentially promising therapy.

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Why Take a Drug That No Longer Gives Pleasure?

September 2015

In mice, a cocaine-induced imbalance in the activity of two key populations of neurons in the reward system persists for a longer period after repeated exposure to the drug. For long-term users, this change could both weaken the cocaine “high” and strengthen the compulsion to seek the drug.

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Teen Foster Care Program Reduces Drug Use in Early Adulthood

September 2015

New findings from a follow-up to a NIDA-supported trial indicate that the benefits of Multidimensional Treatment Foster Care extend to a reduction in illegal drug use in young adulthood.

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THC Hampers Spatial Memory Development in Young Monkeys

September 2015

Adolescent monkeys that were exposed to THC fell progressively further behind THC-free monkeys in their ability to recall the location of an object after a brief delay.

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Brain Imaging Predicts Relapse to Cocaine

September 2015

A NIDA-supported study has found that a cocaine-addicted person’s chance of managing 1 whole year of abstinence correlates with activity levels in these impaired motivational and decision-making brain areas.

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A Rapid Teen Substance Use Screening Tool for Clinicians

July 2015

Answers to three simple questions can help a busy health care provider flag a teen’s problematic use of alcohol, tobacco, or marijuana.

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Electronic Questionnaire Quickly Rates Teens’ Substance Use

July 2015

With a few simple questions, a new screening tool detects whether a teen is likely to have a mild-to-moderate or a severe substance use disorder.

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