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Prescription Opioid Misuse Treatment Leverages Mindfulness To Amplify Natural Rewards

October 2018
Mindfulness-Oriented Recovery Enhancement (MORE) reduces opioid misuse among chronic pain patients. MORE shifts patients' attention away from drug cues and toward cues for natural rewards.

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Switching to Reduced-Nicotine Cigarettes May Aid in Quitting Smoking

October 2018
Smokers who switch to cigarettes with very low nicotine content may experience mild and transient increases in some withdrawal symptoms. Cigarettes with reduced nicotine will be easier to quit than the cigarettes marketed at present.

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How Cocaine Cues Get Planted in the Brain

September 2018
An epigenetic mechanism underlies the powerful cocaine–environment associations that promote relapse.

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Proven Prevention Program Aims To Adapt for Native Americans

August 2018
A survey that is a key tool in the Communities That Care prevention system is largely valid in Native American communities. Adjusting the survey to incorporate culturally specific risk and protective factors can improve its usefulness.

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A New Tool for Investigating HIV in the Brain

August 2018
Researchers developed a tool that enables them to closely monitor HIV activity in key brain cells. The tool may accelerate the development of treatments for HIV in the brain.

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Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

August 2018
Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22.

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E-Cigarettes Promote Smoking Progression in Youth and Depress Quitting Among Adults

August 2018
E-cigarettes are not an effective tool to reduce combustible-cigarette smoking, two NIDA-supported studies indicate.

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Amphetamine Diverts the Brain’s Path to Maturity

July 2018
A key mechanism of adolescent brain development can be disrupted by amphetamine.

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As Opioid Use Disorders Increased, Prescriptions for Treatment Did Not Keep Pace

July 2018
Several effective medications are now available for treating opioid use disorder but many patients who could benefit do not receive them. Some patients who receive the medications face challenges to staying in treatment.

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Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

June 2018
A clinical trial found that patients who self-administered cognitive behavioral therapy (CBT) using computerized training modules reduced their drug use as much as patients who received clinician-delivered CBT, and they maintained this advantage through a 6-month follow-up.

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