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NIDA Notes Articles: Genetics

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PhenX Toolkit Provides Standard Measures for Research

July 2012
NIDA researchers working with human subjects now have a new resource at their fingertips: the PhenX Toolkit’s new Substance Abuse and Addiction (SAA) Collection. The Toolkit is designed to provide standardized measures, vetted and approved by the field, to help researchers compare and combine data from multiple studies.

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Dr. David Jentsch Receives the 2011 Waletzky Memorial Award

July 2012
Dr. J. David Jentsch is the recipient of the 2011 Jacob P. Waletzky Memorial Award for Innovative Research in Drug Addiction and Alcoholism. Dr. Jentsch and colleagues at the University of California, Los Angeles, are studying genetic and neurochemical factors that influence individual differences in inhibitory control.

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Individual Differences in Decisionmaking Style May Predict Teen Problems

December 2011
Reports on the relative influence of genes versus environment on adolescents’ choices that involve delayed gratification.

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Resting Brain Studies Shed New Light on Vulnerabilities

November 2011
Individuals with weak signaling in a nicotine-sensitive brain circuit were more vulnerable to nicotine dependence than those with stronger signaling, according to a study conducted while the subjects’ brains were in a resting state. A second resting-state study finds that the same circuit appears to mediate dependence associated with a genetic risk factor for smoking.

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Gene Influences Impact of Maternal Smoking on Children's Behavioral Problems

July 2011
Describes research showing that the combination of prenatal smoking exposure and specific genes increases children’s and adolescent’s risk for behavior problems.

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Parental Supervision and Genetics Interact To Influence Nicotine Addiction

December 2010
Reviews research indicating that both parental influence and certain genes interact to influence nicotine addiction and that parental monitoring may play a role in reducing risk.

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NIDA Grantee Wins Prize for Genetics Web Sites

December 2010
Announces the recipient of an award for online resources in education, Dr. Louisa Stark, who developed two interactive Web sites on genetics.

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Three Scientists Join Advisory Council

December 2010
Announces three new NIDA National Advisory Council on Drug Abuse members and describes their drug abuse and addiction research experience.

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Workgroup Directs Search for Genes That Influence Addiction

April 2010
Highlights NIDA’s research portfolio to identify the genes and genetic processes responsible for a person’s vulnerability to drug abuse.

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Genetic Overlap Between Substance Abuse and Bipolar Disorder

April 2010
Describes a literature analysis reporting on the prevalence of people with bipolar disorder who also have a substance use disorder and discusses the genetic link that may contribute to this comorbidity.

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