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NIDA Notes Articles: Genetics

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Gene Variant Is Associated With Reduced HIV Transmission

March 2016
A gene variant appears to partially shield people whose behaviors entail high risk for exposure to human immunodeficiency virus (HIV) from becoming infected.

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Gene Variants Reduce Opioid Risks

June 2014
Two recent studies suggest that genotyping may enable clinicians to base therapies on individual patients’ potential responsiveness to opioid drugs’ therapeutic effects and vulnerability to their harmful effects.

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Genetic Overlap Between Substance Abuse and Bipolar Disorder

April 2010
Describes a literature analysis reporting on the prevalence of people with bipolar disorder who also have a substance use disorder and discusses the genetic link that may contribute to this comorbidity.

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Individual Differences in Decisionmaking Style May Predict Teen Problems

December 2011
Reports on the relative influence of genes versus environment on adolescents’ choices that involve delayed gratification.

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Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

August 2013
In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

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Mice With Genetic Alteration Eschew Cocaine

June 2008
Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

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New Technique Links 89 Genes to Drug Dependence

September 2008
Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

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NIDA Grantee Wins Prize for Genetics Web Sites

December 2010
Announces the recipient of an award for online resources in education, Dr. Louisa Stark, who developed two interactive Web sites on genetics.

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NIDA's 35th Anniversary: Science Focused on Solutions

December 2009
Commemorates NIDA’s 35th anniversary and highlights some of the major accomplishments since the Institute’s inception in 1974.

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Parental Supervision and Genetics Interact To Influence Nicotine Addiction

December 2010
Reviews research indicating that both parental influence and certain genes interact to influence nicotine addiction and that parental monitoring may play a role in reducing risk.

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