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NIDA Notes Articles: Comorbidity

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HIV Infection Accelerates Hepatitis C–Related Liver Fibrosis

January 2014
Study patients with HIV­­–hepatitis C coinfection progressed to successive degrees of severity of liver fibrosis 9 years sooner than those infected with HCV alone. Further findings from the study suggest that suppressing HIV with antiretroviral medications may slow HCV-related liver fibrosis.

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Self-Control Protects Urban Minority Youths From Drug Use and Depressive Mood

July 2014
Interventions that bolster self-control in childhood and early adolescence might shield ethnic and racial minority adolescents and young adults from the burden of both drug use and depressive mood.

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Varenicline Helps People With Mental Illness Maintain Abstinence From Smoking

November 2014
The finding from an 18-month-long clinical trial strengthens hope that pharmacotherapy can break nicotine’s especially tenacious hold on people with serious mental illness such as bipolar disorder or schizophrenia.

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Slow-Release Amphetamine Medication Benefits Patients With Comorbid Cocaine Addiction and ADHD

August 2016
Treatment with an extended-release stimulant medication plus cognitive behavioral therapy was associated with reductions in cocaine use and in attention-deficit/hyperactivity disorder symptoms in patients with both disorders.

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Integrated Intervention Benefits People Who Inject Drugs and Have HIV

November 2018
In this international trial, participants who received the intervention engaged in HIV treatment, achieved viral suppression at higher rates, and died at half the rate of participants in a control group.

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