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NIDA Notes Articles: Comorbidity and Mental Health

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Slow-Release Amphetamine Medication Benefits Patients With Comorbid Cocaine Addiction and ADHD

August 2016
Treatment with an extended-release stimulant medication plus cognitive behavioral therapy was associated with reductions in cocaine use and in attention-deficit/hyperactivity disorder symptoms in patients with both disorders.

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Varenicline Helps People With Mental Illness Maintain Abstinence From Smoking

November 2014
The finding from an 18-month-long clinical trial strengthens hope that pharmacotherapy can break nicotine’s especially tenacious hold on people with serious mental illness such as bipolar disorder or schizophrenia.

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Training Workshops Boost Approval of Contingency Management

August 2014
Clinicians associated with the Veterans Administration looked more favorably upon contingency management after attending training workshops on the use of the intervention. Despite being highly effective at decreasing drug use, contingency management is one of the least used among proven substance abuse treatments.

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Self-Control Protects Urban Minority Youths From Drug Use and Depressive Mood

July 2014
Interventions that bolster self-control in childhood and early adolescence might shield ethnic and racial minority adolescents and young adults from the burden of both drug use and depressive mood.

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Dr. Joni Rutter Q&A: How Basic Science Is Tackling Addiction

May 2014
One of NIDA’s goals is to try to understand the individual differences that contribute to whether or not someone who takes a drug will become addicted to it. Dr. Rutter’s research focuses on three types of differences: Environmental, developmental, and genetic and epigenetic.

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HIV Infection Accelerates Hepatitis C–Related Liver Fibrosis

January 2014
Study patients with HIV­­–hepatitis C coinfection progressed to successive degrees of severity of liver fibrosis 9 years sooner than those infected with HCV alone. Further findings from the study suggest that suppressing HIV with antiretroviral medications may slow HCV-related liver fibrosis.

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Study Parses Comorbidity of Cannabis Use and Social Anxiety

October 2013
People with cannabis use disorder (CUD) are likely also to have social anxiety disorder (SAD), and comorbid SAD is associated with greater severity of cannabis-related problems. These findings highlight the importance of assessing CUD patients for SAD, as that disorder can be both a contributing cause and a consequence of CUD. Treating both disorders may be a key to helping patients recover from each.

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Thoughts of Suicide May Persist Among Nonmedical Prescription Opiate Users

March 2013
People who use prescription opiates nonmedically are more likely to consider suicide than those who use these medications only appropriately or not at all. A recent NIDA-supported study also disclosed that the risk for suicidal thoughts remains elevated after cessation of use.

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Intervention Boosts Treatment Participation, Abstinence Among Depressed Women

July 2012
Intensive case management was more effective in increasing treatment engagement and reducing alcohol consumption among depressed participants than among those who were not depressed, according to a followup analysis of a substance abuse treatment study involving women on welfare.

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Program Reduces Recidivism Among Men With Co-occurring Disorders

July 2012
A modified therapeutic community program designed by NIDA-supported researchers helped Colorado offenders with co-occurring substance use and mental health disorders re-enter their communities and avoid recidivism after release from prison.

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