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NIDA Notes Articles: 12-step, Aftercare, Recovery, relapse prevention and Treatment

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Methadone Maintenance Treatment During Incarceration Has Long-Term Benefits

April 2019
Prisoners who received methadone maintenance treatment (MMT) during incarceration were more likely than prisoners who did not receive MMT to engage in the treatment after being released.

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Interim Buprenorphine Alleviates Psychiatric Symptoms in Waitlisted OUD Patients

March 2019
Interim treatment with buprenorphine significantly improved the psychiatric symptoms of people awaiting comprehensive treatment for opioid use disorder (OUD). Buprenorphine treatment, even without concurrent psychosocial counseling, may help patients with no, or delayed, access to comprehensive OUD treatment.

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New Studies Clarify Risk Factors for Neonatal Abstinence Syndrome

January 2019
A recent NIDA-sponsored study found higher rates of NAS among males than among females. A second study found that, among infants whose mothers were treated with buprenorphine while pregnant, NAS was more severe among those whose mothers used other substances.

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Integrated Intervention Benefits People Who Inject Drugs and Have HIV

November 2018
In this international trial, participants who received the intervention engaged in HIV treatment, achieved viral suppression at higher rates, and died at half the rate of participants in a control group. En Español

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As Opioid Use Disorders Increased, Prescriptions for Treatment Did Not Keep Pace

July 2018
Several effective medications are now available for treating opioid use disorder but many patients who could benefit do not receive them. Some patients who receive the medications face challenges to staying in treatment.

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Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

June 2018
A clinical trial found that patients who self-administered cognitive behavioral therapy (CBT) using computerized training modules reduced their drug use as much as patients who received clinician-delivered CBT, and they maintained this advantage through a 6-month follow-up.

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In Animals, Opioid Combination Shows Promise for Safer Pain Relief

June 2018
In rats, the combination treatment of oxycodone/nalfurafine had lower levels of abuse liability and produced less respiratory depression than oxycodone alone.

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Novel Compound Alleviates Hard-to-Treat Pain in Mice

June 2018
A novel compound called GAT211 alleviates inflammatory and neuropathic pain in mice without producing tolerance or signs of abuse liability.

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Cigarette Smoking Increases the Likelihood of Drug Use Relapse

May 2018
Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

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Narrative of Discovery: The Quest for a Medication To Treat Methamphetamine Addiction, Part 3

May 2018
Dr. Linda Dwoskin feels just one small step away from success in her effort to develop the first ever medication to treat methamphetamine addiction.

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