En español

Menu

Home
Drugs of Abuse

Quick Links

Related Topics

Quick Links

Publications

Quick Links

Research

Quick Links

Funding

Quick Links

News

Quick Links

About NIDA

Quick Links

COVID-19 is an emerging, rapidly evolving situation.

Get the latest information from CDC (Coronavirus.gov) | NIH Resources | NIDA Resources

NIDA Notes Articles: Brain and Addiction
NIDA Notes Category Graphic

Machine Learning Applied to Brain Imaging Data Predicts Response to Cocaine Use Disorder Treatment

October 2019
This study demonstrated that functional connectivity among a large number of brain regions predicts patients’ chances of achieving abstinence in treatment for cocaine use disorder.

NIDA Notes Category Graphic

THC Exposure in Adolescence Disrupts Brain Maturation in Animals

August 2019
Exposing adolescent rats to THC disrupted normal maturation of a key set of neurons in a brain area that corresponds to the human prefrontal cortex. The disruptions produced structural differences that resemble patterns which have been observed in people with addiction and schizophrenia.

NIDA Notes Category Graphic

Research Links Adolescent Substance Use to Adult Brain Volumes

April 2019
This research revealed associations between nicotine, alcohol, and marijuana use during two periods of adolescence and smaller gray matter volume in two brain areas at age 25.

NIDA Notes Category Graphic

Transcription Factor E2F3a Mediates Cocaine’s Effects on Gene Expression and Addiction-Related Behaviors

February 2019
This study demonstrated that cocaine increases expression of the protein E2F3a in the brain’s reward system. The changes in E2F3a levels in the nucleus accumbens are tied to addiction-related behaviors and to altered gene expression.

NIDA Notes Category Graphic

Cocaine-Induced Increase in an Immune Protein Promotes Addiction Behaviors in Mice

October 2018
Cocaine produces a portion of its rewarding effects by increasing levels of granulocyte-colony stimulating factor (G-CSF) in the brain’s reward center. Treatments that prevent G-CSF signaling in the nucleus accumbens might reduce motivation to use cocaine.

NIDA Notes Category Graphic

Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

August 2018
Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22. En Español

NIDA Notes Category Graphic

Deep Brain Stimulation Attenuates Rats’ Responses to Heroin

October 2017
High-frequency electrical stimulation of neurons deep in the brain can reduce rats’ relapse-like behavior and motivation to take heroin. The finding strengthens hope that deep brain stimulation might offer a new treatment alternative for opioid addiction, particularly for patients who have not benefited from other treatments.

NIDA Notes Category Graphic

Researchers Speak: The ABCD Study

June 2017
In this video, Dr. Terry Jernigan describes the purpose and goals of the Adolescent Brain and Cognitive Development (ABCD) Study.

NIDA Notes

Categories

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics