En español
NIDA

Menu

Publications

Quick Links

NIDA Notes Articles: Addiction Science

NIDA Notes Category Graphic

EEG Indicates That Cocaine Relapse Vulnerability Peaks 1 to 6 Months Into Abstinence

September 2017
Electroencephalography (EEG) may provide an objective measure of cocaine-addicted participants’ vulnerability to cue-induced relapse. The assessment of cue-induced responsiveness may be useful in the clinical setting for assessing relapse risk and tailoring interventions to maintain abstinence among cocaine-addicted adults. 

NIDA Notes Category Graphic

Endocannabinoid Regulates Cocaine Reward

March 2017
Investigators have shown that 2-AG, an endocannabinoid (i.e., a cannabinoid manufactured within the body, as opposed to plant-derived), augments the cocaine-induced dopamine surge in the brain’s reward system. The discovery adds to evidence that inhibiting activity in the endocannabinoid system might reduce cocaine’s rewarding and addictive effects.  

NIDA Notes Category Graphic

Gene Transfer Therapy for Cocaine Addiction Passes Tests in Animals

January 2016
Giving mice a modified version of a naturally occurring gene blocks cocaine’s stimulant effects without affecting the animals’ physiological or metabolic health. The new evidence advances the proposed therapy a step closer to readiness for testing in people.

NIDA Notes Category Graphic

How Cocaine Cues Get Planted in the Brain

September 2018
An epigenetic mechanism underlies the powerful cocaine–environment associations that promote relapse.

NIDA Notes Category Graphic

Impacts of Drugs on Neurotransmission

March 2017
Drugs can alter the way people think, feel, and behave by disrupting neurotransmission, the process of communication between brain cells. This article discusses the central importance of studying drugs’ effects on neurotransmission and describes some of the most common experimental methods used in this research.  En Español

NIDA Notes Category Graphic

Narrative of Discovery: Can Magnets Treat Cocaine Addiction?

September 2015
Two researchers share their reasons for researching transcranial magnetic stimulation (TMS) for treating cocaine addiction, and describe challenges to moving forward this potentially promising therapy.

NIDA Notes Category Graphic

Narrative of Discovery: Can Magnets Treat Cocaine Addiction? Part 3

March 2017
In the final installment of this series, Dr. Diana Martinez navigates the process for receiving NIH funding to test the efficacy of using transcranial magnetic stimulation as treatment for cocaine addiction.

NIDA Notes Category Graphic

Nonmedical Opioid and Heroin Use Among High School Seniors

April 2017
This study analyzed the use of use of nonmedical opioids and heroin use among 68,000 high-school seniors participating in the NIDA-funded Monitoring the Future Study between 2009 and 2013.

NIDA Notes Category Graphic

Promising Advances in the Search for Safer Opioids

February 2017
New studies show that two novel compounds powerfully suppressed animals’ pain responses, while producing little or none of the respiratory depression and liability for misuse and abuse associated with morphine and other typical opioids.

NIDA Notes Category Graphic

Protein Diminishes Cocaine Reward and Cocaine-Related Learning in Animals

February 2016
The protein acid-sensing ion channel 1A (ASIC1A) is naturally present in the brain and reduces laboratory animals' attraction to environments in which they have experienced cocaine's effects.

Pages

NIDA Notes

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics