En español
NIDA

NIDA Notes Articles: Addiction Science

NIDA Notes Category Graphic

Workgroup Keeps NIDA on the Cutting Edge of Brain Science

December 2010

Reports on the objectives and activities of the Neuroscience Consortium and their impact on Institute drug abuse research programs and initiatives.

NIDA Notes Category Graphic

Workgroup Directs Search for Genes That Influence Addiction

April 2010

Highlights NIDA’s research portfolio to identify the genes and genetic processes responsible for a person’s vulnerability to drug abuse.

NIDA Notes Category Graphic

Women and Sex/Gender Differences Research Program

April 2012

NIDA’s Women and Sex/Gender Differences Research Program focuses on gender-specific addiction risk factors and treatment needs.

NIDA Notes Category Graphic

Why Take a Drug That No Longer Gives Pleasure?

September 2015

In mice, a cocaine-induced imbalance in the activity of two key populations of neurons in the reward system persists for a longer period after repeated exposure to the drug. For long-term users, this change could both weaken the cocaine “high” and strengthen the compulsion to seek the drug.

NIDA Notes Category Graphic

Why Females Are More Sensitive to Cocaine

August 2017

New research demonstrates that the hormone estradiol is responsible for females’ increased sensitivity to stimulant drugs.

NIDA Notes Category Graphic

Why Do People Lose Control Over Their Cocaine Use?

September 2016

Researchers monitored the activity of two types of neurons in mice: “urge” neurons, which promote feelings of reward and repeating behaviors that have produced rewards, and “control” neurons, which dampen those feelings and inhibit behavior.

NIDA Notes Category Graphic

Why Are Our Brains So Big and Powerful?

March 2017

Research suggests that unique patterns of gene regulation have contributed to the differences in brain size and capacity that distinguish humans from other animals.

NIDA Notes Category Graphic

Well-Known Mechanism Underlies Benzodiazepines' Addictive Properties

April 2012

New research establishes that benzodiazepines cause addiction in a way similar to that of opioids, cannabinoids, and the club drug GHB. The discovery opens the door to designing new benzodiazepines that counteract anxiety but are not addictive.

NIDA Notes Category Graphic

Waletzky Memorial Award Winners’ Lectures at NIDA Illuminate Cocaine’s Many Effects on Brain Structure, Circuitry

January 2015

Dr. Paul E. M. Phillips spoke on “Phasic Dopamine Transmission During Substance Abuse,” describing investigations that he has led into the role of brief, seconds-long bursts of dopamine signaling in addictive processes. Dr. Rita Z. Goldstein spoke on “Targeting the Brain, Cognition, and Motivation for Intervention in Addiction.”

NIDA Notes Category Graphic

Variation in the Gene for the μ-Opioid Receptor May Influence Responses to Methadone

August 2017

A single nucleotide polymorphism in the messenger RNA of the µ-opioid receptor gene was associated with patients’ responses to methadone treatment for opioid dependence.

Pages

NIDA Notes

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics