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NIDA Notes Articles: Addiction Science

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Workgroup Keeps NIDA on the Cutting Edge of Brain Science

December 2010

Reports on the objectives and activities of the Neuroscience Consortium and their impact on Institute drug abuse research programs and initiatives.

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Workgroup Directs Search for Genes That Influence Addiction

April 2010

Highlights NIDA’s research portfolio to identify the genes and genetic processes responsible for a person’s vulnerability to drug abuse.

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Women and Sex/Gender Differences Research Program

April 2012

NIDA’s Women and Sex/Gender Differences Research Program focuses on gender-specific addiction risk factors and treatment needs.

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Why Take a Drug That No Longer Gives Pleasure?

September 2015

In mice, a cocaine-induced imbalance in the activity of two key populations of neurons in the reward system persists for a longer period after repeated exposure to the drug. For long-term users, this change could both weaken the cocaine “high” and strengthen the compulsion to seek the drug.

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Why Do People Lose Control Over Their Cocaine Use?

September 2016

Researchers monitored the activity of two types of neurons in mice: “urge” neurons, which promote feelings of reward and repeating behaviors that have produced rewards, and “control” neurons, which dampen those feelings and inhibit behavior.

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Well-Known Mechanism Underlies Benzodiazepines' Addictive Properties

April 2012

New research establishes that benzodiazepines cause addiction in a way similar to that of opioids, cannabinoids, and the club drug GHB. The discovery opens the door to designing new benzodiazepines that counteract anxiety but are not addictive.

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Waletzky Memorial Award Winners’ Lectures at NIDA Illuminate Cocaine’s Many Effects on Brain Structure, Circuitry

January 2015

Dr. Paul E. M. Phillips spoke on “Phasic Dopamine Transmission During Substance Abuse,” describing investigations that he has led into the role of brief, seconds-long bursts of dopamine signaling in addictive processes. Dr. Rita Z. Goldstein spoke on “Targeting the Brain, Cognition, and Motivation for Intervention in Addiction.”

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Universities Offer Online Master's Program in Addiction Studies

April 2009

Describes a consortium of three universities that launched a 12-month intensive online program last August that leads to a master's degree in addiction studies.

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Tracing NET

October 2007

Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.

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Three Scientists Join Advisory Council

December 2010
Announces three new NIDA National Advisory Council on Drug Abuse members and describes their drug abuse and addiction research experience.


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Drugs of Abuse

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