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NIDA Notes Articles: Addiction Science

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A Case for Studying Brain Asymmetry in Drug Use

September 2016
A new study proposes that research into the discrete roles played by the brain’s two hemispheres could yield important and actionable insights into drug use and addiction. Evidence indicates that two risk factors for substance use, impulsivity and craving, primarily reflect activity in the right and left hemispheres, respectively.

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A Gene Links Impulsivity and Drug Use Vulnerability

June 2018
Understanding the relationships between impulsivity and drug use vulnerability may help identify new ways of treating or preventing substance use disorders.

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A Genetic Nexus of Obesity and Smoking

October 2014
Research shows that some gene variants that influence body mass index also shape smoking behaviors.

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Addiction Science Award Winners Announced

December 2010
Announces the 2010 high school student recipients of the Addiction Science Awards and describes their winning addiction-focused projects.

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Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

August 2018
Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22.

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Adolescent Rats Self-Administer More Nicotine Than Adults

April 2009
Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

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Alcohol Abuse Makes Prescription Drug Abuse More Likely

March 2008
Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

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Amphetamine Diverts the Brain’s Path to Maturity

July 2018
A key mechanism of adolescent brain development can be disrupted by amphetamine.

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Animal Study Suggests Marijuana May Affect Future Offspring’s Susceptibility to Heroin

February 2015
Can marijuana use put offspring at heightened risk for opiate addiction, even if the use stops before the offspring are conceived? Results from a recent NIDA-funded study are consistent with other studies suggesting that a parent’s history of drug use, even preconception, may affect a child’s brain function and behavior.

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Animation: Building an Anti-Drug Vaccine

December 2012
The immune system has an extraordinary ability to recognize compounds foreign to the body and eliminate them. NIDA-sponsored scientists are working to harness this ability to create vaccines that will protect individuals against the psychogenic and addictive effects of abused drugs. This animation shows one of the most promising strategies, which has already yielded partial success in producing effective vaccines against nicotine, cocaine, and other drugs.

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