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NIDA Notes Articles: ABCD, Brain, Children, Pre-Teens and Teens

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How Cocaine Cues Get Planted in the Brain

September 2018
An epigenetic mechanism underlies the powerful cocaine–environment associations that promote relapse.

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A New Tool for Investigating HIV in the Brain

August 2018
Researchers developed a tool that enables them to closely monitor HIV activity in key brain cells. The tool may accelerate the development of treatments for HIV in the brain.

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Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

August 2018
Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22.

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A Family-Oriented Intervention May Reduce the Effects of Poverty on Brain Development

January 2018
The parenting-focused Strong African American Families program can ameliorate poverty’s negative effects on limbic brain development.  

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Deep Brain Stimulation Attenuates Rats’ Responses to Heroin

October 2017
High-frequency electrical stimulation of neurons deep in the brain can reduce rats’ relapse-like behavior and motivation to take heroin. The finding strengthens hope that deep brain stimulation might offer a new treatment alternative for opioid addiction, particularly for patients who have not benefited from other treatments.

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Researchers Speak: The ABCD Study

June 2017
In this video, Dr. Terry Jernigan describes the purpose and goals of the Adolescent Brain and Cognitive Development (ABCD) Study.

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Nonmedical Opioid and Heroin Use Among High School Seniors

April 2017
This study analyzed the use of use of nonmedical opioids and heroin use among 68,000 high-school seniors participating in the NIDA-funded Monitoring the Future Study between 2009 and 2013.

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Prevention Program Reduces Substance Use By Participants' Friends

January 2017
The Strengthening Families Program for Youth 10-14 (SFP10-14), an evidence-based intervention that reduces teen substance use, also reduced participants’ friends’ substance use. Two factors that accounted for the nonparticipants’ reductions were less time spent by nonparticipants with their participating friends without adult supervision and improvements in nonparticipants’ attitudes toward substance use. The findings suggest that researchers should consider the potential for diffusion of benefits in designing and implementing prevention programs.

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Study Questions Role for Marijuana in Teen Users’ IQ Decline

August 2016
In a recent study, teens who used marijuana lost IQ points relative to their nonusing peers. However, the drug appeared not to be the culprit.

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Sensation Seeking Promotes Initiation, Impulsivity Promotes Escalation of Substance Use

May 2016
Teens who avidly seek new and intense sensations are more likely to start using substances, but are not more likely to use them regularly within the next 3 years unless they also are prone to devalue distant consequences and act impulsively.

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