En español
NIDA

NIDA Notes Articles: Brain

NIDA Notes Category Graphic

How Cocaine Cues Get Planted in the Brain

September 2018
An epigenetic mechanism underlies the powerful cocaine–environment associations that promote relapse.

NIDA Notes Category Graphic

A New Tool for Investigating HIV in the Brain

August 2018
Researchers developed a tool that enables them to closely monitor HIV activity in key brain cells. The tool may accelerate the development of treatments for HIV in the brain.

NIDA Notes Category Graphic

Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

August 2018
Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22.

NIDA Notes Category Graphic

A Family-Oriented Intervention May Reduce the Effects of Poverty on Brain Development

January 2018
The parenting-focused Strong African American Families program can ameliorate poverty’s negative effects on limbic brain development.  

NIDA Notes Category Graphic

Deep Brain Stimulation Attenuates Rats’ Responses to Heroin

October 2017
High-frequency electrical stimulation of neurons deep in the brain can reduce rats’ relapse-like behavior and motivation to take heroin. The finding strengthens hope that deep brain stimulation might offer a new treatment alternative for opioid addiction, particularly for patients who have not benefited from other treatments.

NIDA Notes Category Graphic

Narrative of Discovery: Can Magnets Treat Cocaine Addiction?

September 2015
Two researchers share their reasons for researching transcranial magnetic stimulation (TMS) for treating cocaine addiction, and describe challenges to moving forward this potentially promising therapy.

NIDA Notes Category Graphic

Why Take a Drug That No Longer Gives Pleasure?

September 2015
In mice, a cocaine-induced imbalance in the activity of two key populations of neurons in the reward system persists for a longer period after repeated exposure to the drug. For long-term users, this change could both weaken the cocaine “high” and strengthen the compulsion to seek the drug.

NIDA Notes Category Graphic

THC Hampers Spatial Memory Development in Young Monkeys

September 2015
Adolescent monkeys that were exposed to THC fell progressively further behind THC-free monkeys in their ability to recall the location of an object after a brief delay.

NIDA Notes Category Graphic

Animation: The Rise and Fall of the Cocaine High

November 2014
This animation shows the rapid passage of cocaine through the brain. It demonstrates that the intensity of the cocaine “high” parallels the trajectory of cocaine levels in the brain.

NIDA Notes Category Graphic

Dr. Antonello Bonci Q & A: Lighting Up the Brain To Shut Down Cocaine Seeking

July 2014
The Scientific Director of NIDA’s Intramural Research Program talks about switching off animals’ compulsive cocaine seeking by optogenetically activating the prefrontal cortex, and the implications of this work for people. In an accompanying podcast, Dr. Bonci walks viewers through experiments that showed that prefrontal cortex activity levels may constitute a simple switch controlling whether or not animals compulsively seek cocaine.

Pages

NIDA Notes

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics