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NIDA Notes Articles: People with Drug Use Disorders

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Social Neuroscience Meeting Aims To Improve Prevention, Treatment

June 2008
Presents highlights of a meeting of scientists and clinicians to review research results from the field of social neuroscience, the study of how neurobiology and the social environment interact.

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Stress Receptor Mediates Lifelong Consequences of Early Trauma

November 2012
NIDA-supported research suggests that glucocorticoid receptor levels during early brain development affect the hard wiring of neural circuits that shape an individual’s basic emotional makeup. In mice, overexpression of the glucocorticoid gene in the first weeks after birth increased anxiety and response to cocaine in adulthood. These findings may help researchers understand the genetic background and the developmental trajectory of addiction.

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Stroop Test Identifies Patients at Risk for Treatment Dropout

April 2010
Reports on a study of cocaine abusers revealing that the Stroop test may predict which cocaine abusers are likely to drop out of therapy.

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Study Endorses Onsite HIV Testing Without Risk Reduction Counseling

April 2013
Patients were more likely to take a rapid HIV test when substance abuse treatment programs offered the test onsite rather than referred for offsite testing. Patients were equally likely to accept and learn their HIV status whether the offer of onsite testing was accompanied by 30 minutes of risk reduction counseling or by 5 minutes of brief information on the testing procedure. Onsite testing accompanied by brief information was cost effective, taking into account the projected lifetime costs of treatment and the gains in health and longevity for detected cases.

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Study Finds Withdrawal No Easier With Ultrarapid Opiate Detox

October 2006
Presents findings from a clinical trial comparing ultrarapid, anesthesia-assisted detoxification with detoxification by traditional methods among patients addicted to heroin.

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Study Gives Green Light to Antiretroviral Medications for HIV-Infected Injection Drug Users

December 2009
Reports finding from a study showing that access to antiretroviral therapies, HAART in particular, can improve the health of HIV-infected patients who have a history of injection drug use.

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Study Parses Comorbidity of Cannabis Use and Social Anxiety

October 2013
People with cannabis use disorder (CUD) are likely also to have social anxiety disorder (SAD), and comorbid SAD is associated with greater severity of cannabis-related problems. These findings highlight the importance of assessing CUD patients for SAD, as that disorder can be both a contributing cause and a consequence of CUD. Treating both disorders may be a key to helping patients recover from each.

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Study Supports Methadone Maintenance in Therapeutic Communities

December 2010
Describes a study that examined the effectiveness of combining two therapies for drug abuse addiction: methadone treatment and therapeutic communities, two approaches that are rarely combined.

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Substance Abuse and Sexual Risk Show Town-Gown Divide

December 2009
Compares data on substance abuse and sexual risk among college students and their peers who do not attend college.

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Suiting Treatment to the Nature of the Disease

October 2009
Highlights NIDA-sponsored research underway to understand and respond to substance abusers’ needs at all points of care, from the initial presentation for treatment through recovery.

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