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NIDA Notes Articles: People with Drug Use Disorders

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Chromosome 17 Harbors Opioid Dependence Genes

March 2008
Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

March 2008
Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

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Cocaine Abusers' Pretreatment Cue Responses Predict Recovery Success

February 2007
Reports on the work of researchers who used brain images to correlate cocaine-addicted patients' regional brain responses to drug cues with their outcomes in subsequent treatment.

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Cocaine Locks Rats Into Unrewarding Behaviors

April 2009
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Cocaine Vaccine Helps Some Reduce Drug Abuse

December 2010
Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

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Combination Treatment Extends Marijuana Abstinence

March 2008
Describes research investigating the use of a treatment that combines vouchers and cognitive behavioral therapy as compared with the use of either treatment alone for marijuana abuse.

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Combined Treatments Improve Dual Abstinence

October 2009
Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

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Computer-Based Intervention Offers Good Value for Money

July 2011
Reports on researchers who demonstrated the economic value of a computer-based treatment as an adjunct to standard addiction therapy.

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Computer-Based Interventions Promote Drug Abstinence

November 2009
Discusses the work of researchers who have begun to harness the potential of computers to reinforce and expand upon the well-established benefits of recovery therapy delivered by a counselor.

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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment

April 2009
Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

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