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NIDA Notes Articles: People with Drug Use Disorders

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Study Endorses Onsite HIV Testing Without Risk Reduction Counseling

April 2013
Patients were more likely to take a rapid HIV test when substance abuse treatment programs offered the test onsite rather than referred for offsite testing. Patients were equally likely to accept and learn their HIV status whether the offer of onsite testing was accompanied by 30 minutes of risk reduction counseling or by 5 minutes of brief information on the testing procedure. Onsite testing accompanied by brief information was cost effective, taking into account the projected lifetime costs of treatment and the gains in health and longevity for detected cases.

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Stroop Test Identifies Patients at Risk for Treatment Dropout

April 2010
Reports on a study of cocaine abusers revealing that the Stroop test may predict which cocaine abusers are likely to drop out of therapy.

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Stress Receptor Mediates Lifelong Consequences of Early Trauma

November 2012
NIDA-supported research suggests that glucocorticoid receptor levels during early brain development affect the hard wiring of neural circuits that shape an individual’s basic emotional makeup. In mice, overexpression of the glucocorticoid gene in the first weeks after birth increased anxiety and response to cocaine in adulthood. These findings may help researchers understand the genetic background and the developmental trajectory of addiction.

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Social Neuroscience Meeting Aims To Improve Prevention, Treatment

June 2008
Presents highlights of a meeting of scientists and clinicians to review research results from the field of social neuroscience, the study of how neurobiology and the social environment interact.

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Seek-Test-Treat-Retain To Stop the Spread of HIV

February 2013
Despite the advances in treatment and prevention, roughly 50,000 new HIV infections still occur annually in the Nation. Research, in large part supported by NIDA, has produced a strategy to address this circumstance and break the epidemiological impasse: seek out HIV-infected individuals, particularly those in “hard-to-reach” groups that have minimal contact with the health care system; offer them HIV testing and treatment; and provide support to help them stay in treatment.

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Resting Brain Studies Shed New Light on Vulnerabilities

November 2011
Individuals with weak signaling in a nicotine-sensitive brain circuit were more vulnerable to nicotine dependence than those with stronger signaling, according to a study conducted while the subjects’ brains were in a resting state. A second resting-state study finds that the same circuit appears to mediate dependence associated with a genetic risk factor for smoking.

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Report Calls for Sweeping Changes in Health Care for Mental and Substance Abuse Problems

February 2007
Reviews a report from the National Academy of Sciences’ Institute of Medicine that discusses ways to improve the quality of health care among people with mental health and substance abuse disorders.

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Reducing Postpartum Drug Use

December 2008
Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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Reduced Longevity Among Male Heroin Abusers, 1962-1997

June 2008
Reviews the changing lifespan of heroin abusers as compared with that of the general U.S. population based on 1962-1997 data.

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Recovery Checkup System Helps Substance Abusers Who Have Mental Disorders

December 2009
Reports on a posttreatment intervention to support recovery that may be especially beneficial for substance abusers with co-occurring mental disorders.

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