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NIDA Notes Articles: People with Drug Use Disorders

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Methamphetamine Abusers Show Increased Distractibility

April 2009
Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.

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Legal Pressure Increases Treatment Retention

April 2009
Presents data on the length of stay in substance abuse treatment among people who were in treatment as a result of legal pressure as compared with those in treatment voluntarily.

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Cocaine Locks Rats Into Unrewarding Behaviors

April 2009
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment

April 2009
Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

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Damage to Brain Area May Immediately Halt Cigarette Addiction

April 2009
Describes a study among people who had sustained brain injuries to investigate whether certain damaged areas of the brain are associated with the ability to quit smoking.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers

October 2009
Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Methamphetamine Abuse Alters Response to Facial Cues

October 2009
Highlights research showing methamphetamine abusers may have more difficulty than nonabusers in responding with empathy and self-control to people who are experiencing intense emotions.

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Suiting Treatment to the Nature of the Disease

October 2009
Highlights NIDA-sponsored research underway to understand and respond to substance abusers’ needs at all points of care, from the initial presentation for treatment through recovery.

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Combined Treatments Improve Dual Abstinence

October 2009
Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

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Most People Entering Drug Treatment Have Additional Mental Health Problems

November 2009
Highlights data on the prevalence of people entering substance abuse treatment programs who also reported having at least one co-occurring mental health problem.

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