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NIDA Notes Articles: People with Drug Use Disorders

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Reduced Longevity Among Male Heroin Abusers, 1962-1997

June 2008
Reviews the changing lifespan of heroin abusers as compared with that of the general U.S. population based on 1962-1997 data.

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Intervention Improves Employment Outlook For Methadone Patients

June 2008
Describes a study of unemployed methadone patients and the use of assertive outreach and motivational techniques to improve the patients’ employment outlook.

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Lofexidine May Enhance Naltrexone Efficacy

December 2008
Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008
Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Methadone Reduces Rats' Cocaine Seeking

December 2008
Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Reducing Postpartum Drug Use

December 2008
Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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Cocaine Locks Rats Into Unrewarding Behaviors

April 2009
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Methamphetamine Abusers Show Increased Distractibility

April 2009
Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.

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Legal Pressure Increases Treatment Retention

April 2009
Presents data on the length of stay in substance abuse treatment among people who were in treatment as a result of legal pressure as compared with those in treatment voluntarily.

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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment

April 2009
Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

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