Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.
Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.
Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.
Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.
Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.
Describes new tools under development, including one to visualize cells deep in the brain and another one that remotely activates brain cells.
Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.
Describes research findings demonstrating that the immune system participates in the shaping of brain circuits during a child's development, a finding that may shed light on the origins of neurodegenerative diseases.
Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.