Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.
Describes a new chemical tracer that binds specifically to cannabinoid receptors making it potentially useful in future research to clarify the relationship between the receptors and drug abuse.
Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.
Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.
Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.
Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.
Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.
Reports on scientists who pinpointed the biochemical trigger from morphine that sets off a chain reaction that inhibits an immune cell that is key in fighting viruses and cancer.
Reports on research showing that newborns whose mothers abused methamphetamine during pregnancy showed lower rates of fetal growth as compared with unexposed newborns.
Reports on evidence that toluene abuse can harm the nervous system and body, although scientists know relatively little about its specific actions.