Highlights data from an annual national survey of youth showing a pattern of rising nonmedical use of sedatives among high school seniors.
Summarizes research suggesting a physiological difference as the explanation for African-Americans' reported low tolerance for pain.
Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.
Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.
Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.
Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.
Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.
Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.
Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.