October 2006 Highlights data from an annual national survey of youth showing a pattern of rising nonmedical use of sedatives among high school seniors.
October 2006 Summarizes research suggesting a physiological difference as the explanation for African-Americans' reported low tolerance for pain.
February 2007 Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.
February 2007 Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.
February 2007 Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.
April 2007 Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.
October 2007 Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.
October 2007 Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.
October 2007 Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.
October 2007 Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.