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NIDA Notes Articles: Public Health

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Blocking Protein Complex May Lock Down HIV Reservoirs

September 2017
Inhibiting mTOR, a regulatory protein complex, can prevent reactivation of latent HIV. Medications to inhibit mTOR might help people with HIV achieve and maintain undetectable HIV viral loads.

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Substance Use Disorders Are Associated With Major Medical Illnesses and Mortality Risk in a Large Integrated Health Care System

October 2017
Strong associations exist between substance use disorder diagnoses and 19 major medical illnesses among patients in a large, integrated health care system. The study indicates that these associations may persist even in health care systems that provide specialized treatment for substance use disorders and have capacity to integrate behavioral and medical care.

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Anabolic-Androgenic Steroids May Damage the Heart and Arteries

November 2017
Use of anabolic-androgenic steroids (AAS) is associated with compromised heart pumping and atherosclerotic plaque. Clinicians should inquire about AAS use when young or middle-aged men present with left ventricular dysfunction or coronary artery disease.

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Available Soon: NIDA’s E-Cigarette

January 2018
NIDA and NJOY, LLC, have developed a Standard Research E-Cigarette. The device will help researchers resolve many outstanding questions about how e-cigarettes affect health.

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Stressful Experiences Affect Likelihood of Remission of Drug Dependence, Continued Drug Use, and Relapse

February 2018
Stressful life events are associated with reductions in a person’s chances of becoming or remaining abstinent from drugs for at least 3 years.

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Long-Term Marijuana Use Is Associated With Health Problems Later in Life

February 2018
Researchers used the statistical technique of latent class analysis to describe distinct patterns of marijuana use across age using data from nearly 10,000 participants in the Monitoring the Future study. Longer-term marijuana use (extending from age 18 into the late 20s or beyond) was associated with increased risk of self-reported health problems at age 50.

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