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NIDA Notes Articles: Treatment

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Fear of Distress Signals Risk for Opioid Misuse in Chronic Pain Patients

April 2018
Among patients with chronic pain, those who reported less ability to tolerate physical or emotional distress were more likely to misuse opioid analgesics.

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Electronic Questionnaire Quickly Rates Teens’ Substance Use

July 2015
With a few simple questions, a new screening tool detects whether a teen is likely to have a mild-to-moderate or a severe substance use disorder.

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ED-Initiated Buprenorphine Outperforms Referral or SBIRT for ED Patients With Opioid Addiction

January 2016
Emergency department visits present prime opportunities to identify people with opioid addiction and provide them with onsite initiation of treatment with buprenorphine/naloxone.

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Dual Regimen Aims To Shorten Medication-Assisted Therapy

May 2016
Treatment that combines use of Bp/Nx and memantine may enable young adults addicted to opioids establish lasting abstinence after a relatively brief course of medication-assisted therapy, a pilot trial suggests.

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Dr. Thomas Kosten Q & A: Vaccines To Treat Addiction

June 2015
In this article and accompanying podcast, Dr. Thomas Kosten discusses the idea and current status of antidrug vaccines to treat substance use and addiction.

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Distinct Challenges Affect Women’s HIV Treatment Outcomes After Jail

May 2015
Women who are infected with HIV and are transitioning back to communities after serving jail time are less likely than their male counterparts to have a regular HIV care provider, to take and regularly adhere to an HIV medication regimen, and to have suppression of the virus.

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Digital Addiction Therapies Affirm Promise in Replication and Large Trial

November 2015
Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.

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Deep Brain Stimulation Attenuates Rats’ Responses to Heroin

October 2017
High-frequency electrical stimulation of neurons deep in the brain can reduce rats’ relapse-like behavior and motivation to take heroin. The finding strengthens hope that deep brain stimulation might offer a new treatment alternative for opioid addiction, particularly for patients who have not benefited from other treatments.

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Cigarette Smoking Increases the Likelihood of Drug Use Relapse

May 2018
Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

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Buprenorphine Benefits Waitlisted Seekers of Opioid Treatment

March 2017
In two pilot clinical trials, buprenorphine helped participants reduce their illicit opioid use and injection drug use while awaiting admission to a methadone or buprenorphine treatment program. Researchers minimized the risks for improper use or diversion of the study medication by giving it to trial participants in a computerized, tamper-proof device that dispenses one dose each day.

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