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NIDA Notes Articles: Smoking

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A Genetic Nexus of Obesity and Smoking

October 2014
Research shows that some gene variants that influence body mass index also shape smoking behaviors.

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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize

October 2009
Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.

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Adolescent Cigarette, Alcohol Use Declines as Marijuana Use Rises

February 2013
Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling  trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.

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Adolescent Smoking and Drinking at Historic Lows

July 2012
Rates of adolescent cigarette smoking and alcohol drinking stood at historic lows in 2011, but marijuana use trended upward, according to the Monitoring the Future (MTF) survey.

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Behavioral Problems Related to Maternal Smoking During Pregnancy Manifest Early in Childhood

June 2008
Describes research providing evidence that maternal smoking during pregnancy contributes to behavioral conduct disorders among toddlers, school-age children, and teens.

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Cigarette Smoking Increases the Likelihood of Drug Use Relapse

May 2018
Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

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Cognitive Strategy Reduces Craving by Altering Brain Activity

April 2012
While viewing images of cigarettes, smokers reported milder cravings when they shifted their focus from the pleasures of smoking to its harmful effects. Brain imaging showed a correlation between the reductions in craving and altered activity levels in regions associated with emotional regulation and reward.

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Combination Therapy Most Effective for Helping Smokers Quit

March 2011
Examines results from a randomized clinical trial which found that treatment with a nicotine patch and nicotine lozenge together produced the greatest benefits in helping people quit smoking and remain abstinent.

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Desire to Smoke Subsides, But Cigarette Cues Retain Power

April 2012
During early abstinence, smokers’ cravings triggered by cigarette cues intensified over time, providing evidence that people can experience a phenomenon previously observed in experiments with animals

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Dr. Joni Rutter Q&A: How Basic Science Is Tackling Addiction

May 2014
One of NIDA’s goals is to try to understand the individual differences that contribute to whether or not someone who takes a drug will become addicted to it. Dr. Rutter’s research focuses on three types of differences: Environmental, developmental, and genetic and epigenetic.

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