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NIDA Notes Articles: Smoking

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Switching to Reduced-Nicotine Cigarettes May Aid in Quitting Smoking

October 2018
Smokers who switch to cigarettes with very low nicotine content may experience mild and transient increases in some withdrawal symptoms. Cigarettes with reduced nicotine will be easier to quit than the cigarettes marketed at present.

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E-Cigarettes Promote Smoking Progression in Youth and Depress Quitting Among Adults

August 2018
E-cigarettes are not an effective tool to reduce combustible-cigarette smoking, two NIDA-supported studies indicate.

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Cigarette Smoking Increases the Likelihood of Drug Use Relapse

May 2018
Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

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Varenicline Helps People With Mental Illness Maintain Abstinence From Smoking

November 2014
The finding from an 18-month-long clinical trial strengthens hope that pharmacotherapy can break nicotine’s especially tenacious hold on people with serious mental illness such as bipolar disorder or schizophrenia.

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Smoking Cessation Does Not Interfere With Recovery From Substance Use

October 2014
Despite common concerns that encouraging patients to quit smoking might endanger their success in treatment of substance use and mood or anxiety disorders, smoking cessation appears unlikely to hinder and may even help recovery.

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A Genetic Nexus of Obesity and Smoking

October 2014
Research shows that some gene variants that influence body mass index also shape smoking behaviors.

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Dr. Joni Rutter Q&A: How Basic Science Is Tackling Addiction

May 2014
One of NIDA’s goals is to try to understand the individual differences that contribute to whether or not someone who takes a drug will become addicted to it. Dr. Rutter’s research focuses on three types of differences: Environmental, developmental, and genetic and epigenetic.

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Marijuana Use May Promote Nicotine Consumption

April 2014
Exposing rats to THC increases the likelihood that the animals will later self-administer nicotine. THC-exposed rats are also willing to work harder to obtain nicotine. When extrapolated to people, the findings suggest that THC’s pharmacological impact on the brain may make a person who uses marijuana more vulnerable to developing nicotine addiction, an underappreciated health consequence of marijuana use.

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