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NIDA Notes Articles: Stimulants

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Crack Cocaine Promotes Progression of HIV Infection to AIDS

October 2010
Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.

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Deep Brain Stimulation Reduces Rats' Cocaine Seeking

December 2010
Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.

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Disruption of Neuron Production in Adult Rats Increases Cocaine Taking

November 2011
Drug abuse may diminish production of new neurons in the brain’s hippocampus and thereby increase vulnerability to drug addiction.

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Drugs Contribute to High Rates of Sexually Transmitted Diseases Among Juvenile Offenders

July 2011
Describe a study of newly arrested youths where researchers found correlations between the youths' prevalence of these sexually transmitted diseases and their cocaine and marijuana use.

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Fewer Young Adults Abuse Cocaine and Methamphetamine, National Survey Finds

December 2008
Reports prevalence rates of illicit drug abuse among youths and young adults based on 2007 data from a national survey of drug use and health.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance

April 2007
Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Long-Term Cocaine Self-Administration Depresses Brain Activity

December 2008
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction

April 2009
Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment

October 2006
Reports on a study investigating the use of incentives in the form of prizes to motivate outpatients to stay in behavioral therapy and remain drug free.

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Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

August 2013
In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

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