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NIDA Notes Articles: Stimulants

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Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment

October 2006
Reports on a study investigating the use of incentives in the form of prizes to motivate outpatients to stay in behavioral therapy and remain drug free.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance

April 2007
Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Cocaine Can Mobilize Stored Dopamine

March 2008
Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Methadone Reduces Rats' Cocaine Seeking

December 2008
Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Fewer Young Adults Abuse Cocaine and Methamphetamine, National Survey Finds

December 2008
Reports prevalence rates of illicit drug abuse among youths and young adults based on 2007 data from a national survey of drug use and health.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

December 2008
Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008
Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction

April 2009
Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Cocaine Locks Rats Into Unrewarding Behaviors

April 2009
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Methadone Therapy in Prison Benefits Men a Year Out

November 2009
Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

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