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NIDA Notes Articles: Opioids

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Detoxification Services and Pharmacotherapies Lacking in Nation's Jails and Prisons

December 2010
Reports findings from a survey that revealed that although substance abuse is prevalent in jails and prisons, many correctional facilities do not offer detoxification services or therapies to aid in maintaining abstinence.

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Digital Addiction Therapies Affirm Promise in Replication and Large Trial

November 2015
Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.

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Dr. Evan D. Kharasch Joins the Institute of Medicine

December 2013
Dr. Kharasch is a NIDA-funded researcher known for a broad range of research into how drugs are metabolized in the body.

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Dr. Marilyn Huestis Q & A: Matching Drug Effects to Drug Concentrations

September 2013
Dr. Marilyn Huestis of NIDA’s Intramural Research Program talks about conducting research on drug effects with human subjects, developing tests to help law enforcement identify drugged drivers, and an assay to help identify children whose prenatal exposure to anti-HIV drugs may put them at risk for adverse developmental outcomes.

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Dual Regimen Aims To Shorten Medication-Assisted Therapy

May 2016
Treatment that combines use of Bp/Nx and memantine may enable young adults addicted to opioids establish lasting abstinence after a relatively brief course of medication-assisted therapy, a pilot trial suggests.

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ED-Initiated Buprenorphine Outperforms Referral or SBIRT for ED Patients With Opioid Addiction

January 2016
Emergency department visits present prime opportunities to identify people with opioid addiction and provide them with onsite initiation of treatment with buprenorphine/naloxone.

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Expanded HIV Screening Projected To Decrease Spread of the Virus

April 2014
Intensified screening for HIV among injection drug users receiving opioid agonist therapy could prevent more than twice as many new infections as current screening practice. A recent study based on mathematical modeling found that screening every 6 months instead of annually, and adding viral RNA testing to the currently used HIV antibody testing, could improve both effectiveness and cost-effectiveness.

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Few Teens With Prescription Opioid Use Disorders Receive Treatment

July 2012
Fewer than 12 percent of adolescents who meet diagnostic criteria for prescription opioid abuse or dependence receive any treatment, according to an analysis of data from the 2005 to 2008 National Survey on Drug Use and Health. The most common reason the adolescents gave for not receiving treatment was their lack of perceived need for it.

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First-time Patients Opt for Office-Based Buprenorphine

October 2006
Presents highlights of a study suggesting that compared with methadone, office-based buprenorphine treatment attracts individuals who have less extensive addiction histories.

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Gene Variants Reduce Opioid Risks

June 2014
Two recent studies suggest that genotyping may enable clinicians to base therapies on individual patients’ potential responsiveness to opioid drugs’ therapeutic effects and vulnerability to their harmful effects.

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