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NIDA Notes Articles: Tobacco

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008
Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving

December 2008
Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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Behavioral Problems Related to Maternal Smoking During Pregnancy Manifest Early in Childhood

June 2008
Describes research providing evidence that maternal smoking during pregnancy contributes to behavioral conduct disorders among toddlers, school-age children, and teens.

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Teen Substance Abuse Continues to Decline

March 2008
Reports on the prevalence of substance abuse among youth based on 2007 data from a national survey of behaviors, attitudes, and values.

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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

October 2007
Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

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Vaccine May Reduce Fetal Exposure to Nicotine

April 2007
Describes research on a vaccine developed to facilitate smoking cessation by blocking nicotine penetration into the brain.

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Genes and Smoking

April 2007
Reports on the research underway to identify gene variations associated with nicotine addiction and the interaction of genetic makeup, experiences, and surroundings to addiction.

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Naltrexone-Nicotine Patch Combination Shows Promise

April 2007
Reports findings from a clinical trial investigating the effectiveness of naltrexone as a supplement to nicotine replacement therapy for smoking cessation.

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Standard Treatments Help Depressed Smokers Quit

April 2007
Describes a study comparing Staged Care Intervention, a combination treatment for smoking cessation, among smokers in outpatient treatment for depression and a control group.

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Addiction and Co-Occurring Mental Disorders

February 2007
Presents an overview of the research underway to investigate medication and behavioral therapies for co-occurring disorders.

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