En español

Menu

Publications

Quick Links

NIDA Notes Articles: Marijuana

NIDA Notes Category Graphic

Adolescent Marijuana Use Is Linked to Altered Neural Circuitry and Mood Symptoms

August 2018
Some teens' marijuana use has been linked to disrupted communication between two key regions in the brain’s reward circuitry at age 20. Disrupted communication between the regions was associated with poorer psychosocial functioning at age 22. En Español

NIDA Notes Category Graphic

After Showing Promise for Cannabis-Using Adolescents, N-Acetylcysteine Falters in Adult Study

September 2017
In a clinical trial, N-acetylcysteine did not help adults reduce their cannabis use, despite having been effective for adolescents in a previous trial. The results indicated that if adults are able to benefit from the medication, they will likely require a different treatment regimen than adolescents.

NIDA Notes Category Graphic

Animal Study Suggests Marijuana May Affect Future Offspring’s Susceptibility to Heroin

February 2015
Can marijuana use put offspring at heightened risk for opiate addiction, even if the use stops before the offspring are conceived? Results from a recent NIDA-funded study are consistent with other studies suggesting that a parent’s history of drug use, even preconception, may affect a child’s brain function and behavior.

NIDA Notes Category Graphic

Cannabis Dependence Is Associated With Changes in Neural Circuitry That May Contribute to Psychopathology

May 2019
People with cannabis dependence have changes in neural circuitry in brain regions related to reward processing, habit formation, and psychopathology. These changes in neural circuitry may provide a useful marker for tracking psychopathology associated with cannabis misuse.

NIDA Notes Category Graphic

Drug Use and Its Consequences Increase Among Middle-Aged and Older Adults

July 2019
The spread of marijuana use and the opioid epidemic over the past 10 years have affected middle-aged and older Americans. In addition, prescription opioid and benzodiazepine misuse increased older adults’ risk of suicidal thoughts.

NIDA Notes Category Graphic

Long-Term Marijuana Use Is Associated With Health Problems Later in Life

February 2018
Researchers used the statistical technique of latent class analysis to describe distinct patterns of marijuana use across age using data from nearly 10,000 participants in the Monitoring the Future study. Longer-term marijuana use (extending from age 18 into the late 20s or beyond) was associated with increased risk of self-reported health problems at age 50. En Español

NIDA Notes Category Graphic

Nicotine and Cannabis Have Offsetting Effects on Resting Brain Connectivity

June 2019
These findings add to research showing that nicotine and cannabis have interactive effects on brain structure and function. They also suggest that specialized treatment interventions may be appropriate for people who use both drugs.

NIDA Notes Category Graphic

Regular Marijuana Use Is Associated With Differences in Brain Gray Matter and Connectivity

September 2016
A brain imaging study strongly suggests that regular users of marijuana have smaller orbitofrontal cortex (OFC) volumes. Such a deficit could make it more difficult to change counterproductive behaviors, including drug use.

NIDA Notes Category Graphic

Research Links Adolescent Substance Use to Adult Brain Volumes

April 2019
This research revealed associations between nicotine, alcohol, and marijuana use during two periods of adolescence and smaller gray matter volume in two brain areas at age 25.

NIDA Notes Category Graphic

Study Links Medical Marijuana Dispensaries to Reduced Mortality From Opioid Overdose

May 2016
Legally protected marijuana dispensaries (LMDs) were associated with lower rates of dependence on prescription opioids, and deaths due to opioid overdose, than would have been expected based on prior trends. However, LMDs also were associated with higher rates of recreational marijuana use and increased potency of illegal marijuana.

Pages

NIDA Notes

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics