November 2011 Drug abuse may diminish production of new neurons in the brain’s hippocampus and thereby increase vulnerability to drug addiction.
Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.
December 2010 Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.
October 2010 Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.
Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.
Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.
Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.
Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.
February 2007 Reports on the work of researchers who used brain images to correlate cocaine-addicted patients' regional brain responses to drug cues with their outcomes in subsequent treatment.