October 2006 Describes a series of experiments that have added to evidence that a brain enzyme controls key memory processes that link drug experiences, the surroundings in which they take place, and the urge to repeat them.
October 2006 Describes an inpatient study investigating the effectiveness of sustained-release methylphenidate as a treatment for cocaine-addiction patients with ADHD.
February 2007 Describes evidence supporting the view that developmental differences in brain systems that use the neurotransmitter dopamine underlie age differences in susceptibility to drug abuse.
February 2007 Reports on the work of researchers who used brain images to correlate cocaine-addicted patients' regional brain responses to drug cues with their outcomes in subsequent treatment.
April 2007 Describes investigations to advance the development of potential drug abuse relapse prevention agents by targeting specific receptors of the neurochemical serotonin.
April 2007 Reports on data that reviewing the benefits of addiction treatment among abstinent men as compared with those who continued to abuse cocaine.
March 2008 Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.
March 2008 Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.
March 2008 Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.
June 2008 Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.