En español
NIDA

NIDA Notes Articles: Cocaine

NIDA Notes Category Graphic

Testing a Prospective Medication To Help People Avoid Relapse

March 2016

This NIDA Notes animation depicts a basic experiment that researchers use to test whether a prospective new medication can prevent relapse to drug addiction.

NIDA Notes Category Graphic

Protein Diminishes Cocaine Reward and Cocaine-Related Learning in Animals

February 2016

The protein acid-sensing ion channel 1A (ASIC1A) is naturally present in the brain and reduces laboratory animals' attraction to environments in which they have experienced cocaine's effects.

NIDA Notes Category Graphic

Gene Transfer Therapy for Cocaine Addiction Passes Tests in Animals

January 2016

Giving mice a modified version of a naturally occurring gene blocks cocaine’s stimulant effects without affecting the animals’ physiological or metabolic health. The new evidence advances the proposed therapy a step closer to readiness for testing in people.

NIDA Notes Category Graphic

Digital Addiction Therapies Affirm Promise in Replication and Large Trial

November 2015

Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.

NIDA Notes Category Graphic

Narrative of Discovery: Can Magnets Treat Cocaine Addiction?

September 2015

Two researchers share their reasons for researching transcranial magnetic stimulation (TMS) for treating cocaine addiction, and describe challenges to moving forward this potentially promising therapy.

NIDA Notes Category Graphic

Why Take a Drug That No Longer Gives Pleasure?

September 2015

In mice, a cocaine-induced imbalance in the activity of two key populations of neurons in the reward system persists for a longer period after repeated exposure to the drug. For long-term users, this change could both weaken the cocaine “high” and strengthen the compulsion to seek the drug.

NIDA Notes Category Graphic

Brain Imaging Predicts Relapse to Cocaine

September 2015

A NIDA-supported study has found that a cocaine-addicted person’s chance of managing 1 whole year of abstinence correlates with activity levels in these impaired motivational and decision-making brain areas.

NIDA Notes Category Graphic

Study Ranks Recovery Assets in Cocaine Addiction

July 2015

A can-do attitude, ability to cope with potential triggers for drug use, readiness to change, and participation in self-help programs are major assets for people trying to recover from cocaine addiction.

NIDA Notes Category Graphic

Dr. Thomas Kosten Q & A: Vaccines To Treat Addiction

June 2015

In this article and accompanying podcast, Dr. Thomas Kosten discusses the idea and current status of antidrug vaccines to treat substance use and addiction.

NIDA Notes Category Graphic

Stress Hormone Sets the Stage for Relapse to Cocaine Use

June 2015

A stressed rat will seek a dose of cocaine that is too weak to motivate an unstressed rat. Researchers traced the physiological pathway that links stress and the stress hormone corticosterone to increased dopamine activity and heightened responsiveness to cocaine.

Pages

NIDA Notes

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics