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NIDA Notes Articles: Alcohol

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Researchers Identify Rare Gene Variants Associated With Smoking and Alcohol Use

May 2020
International research teams analyzed several hundred thousand samples from 17 whole-exome sequencing studies to identify rare gene variants associated with smoking and alcohol use. They identified rare variants in 117 DNA regions as being associated with specific aspects of nicotine and alcohol use, including some in genes already known to influence these traits.

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AOUD Treatment in Primary Care Settings—Is it Feasible?

January 2020
Treatment for alcohol and opioid use disorders (AOUD) is feasible in primary care settings, but ongoing funding to support organizational capacity is critical for sustaining such programs.

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Research Links Adolescent Substance Use to Adult Brain Volumes

April 2019
This research revealed associations between nicotine, alcohol, and marijuana use during two periods of adolescence and smaller gray matter volume in two brain areas at age 25.

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Prevention Program Reduces Substance Use By Participants' Friends

January 2017
The Strengthening Families Program for Youth 10-14 (SFP10-14), an evidence-based intervention that reduces teen substance use, also reduced participants’ friends’ substance use. Two factors that accounted for the nonparticipants’ reductions were less time spent by nonparticipants with their participating friends without adult supervision and improvements in nonparticipants’ attitudes toward substance use. The findings suggest that researchers should consider the potential for diffusion of benefits in designing and implementing prevention programs.

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