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NIDA Notes Articles: Withdrawal

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More Convenient Preparations of Buprenorphine Pass Test

July 2012
Soluble-film preparations of buprenorphine suppressed heroin abusers’ withdrawal symptoms with no serious side effects in a recent clinical trial. They dissolved more rapidly in the mouth than the pill form of the medication, providing faster relief.

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Gabapentin Tested To Treat Marijuana Dependence

April 2013
Marijuana-dependent outpatients who were treated with the medication gabapentin in a pilot clinical trial reduced their cannabis use more and reported fewer symptoms of drug withdrawal than patients who received a placebo.

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Receptor May Underlie Gender Differences in Response to Smoking Cessation

May 2013
Men benefit more than women from nicotine replacement therapy for smoking cessation because nicotine affects a key neuroreceptor differently in the two sexes, a NIDA-sponsored study suggests. The findings highlight the need for alternative therapies for women smokers, and point to the female hormone progesterone as a potential therapeutic target.

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Patients Addicted to Opioid Painkillers Achieve Good Results With Outpatient Detoxification

February 2015
A significant portion of individuals who are addicted to opioid painkillers may initiate and maintain abstinence with a brief but intensive outpatient detoxification treatment followed by opioid antagonist therapy using naltrexone.

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