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NIDA Notes Articles: Treatment Research

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Nanotechnology Powers Smart Skin Patch

November 2011
An in vitro test demonstrates the potential of a programmable skin patch that will enable physicians to tailor transdermal medication doses to match patients' fluctuating needs.

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Narrative of Discovery: Can Magnets Treat Cocaine Addiction?

September 2015
Two researchers share their reasons for researching transcranial magnetic stimulation (TMS) for treating cocaine addiction, and describe challenges to moving forward this potentially promising therapy.

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Narrative of Discovery: Can Magnets Treat Cocaine Addiction? Part 2

July 2016
During investigations into using transcranial brain stimulation (TMS) to treat cocaine abuse, two projects take diverging paths. One researcher moves to the next stage, while another is forced to cut his trial short. 

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Narrative of Discovery: Can Magnets Treat Cocaine Addiction? Part 3

March 2017
In the final installment of this series, Dr. Diana Martinez navigates the process for receiving NIH funding to test the efficacy of using transcranial magnetic stimulation as treatment for cocaine addiction.

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Narrative of Discovery: In Search of a Medication To Treat Methamphetamine Addiction

January 2015
This is the first in a series of NIDA Notes articles that will follow a team of researchers seeking a medication for methamphetamine addiction. This installment describes the early promise of the compound lobeline and the new directions the team discovered in studying it.

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Narrative of Discovery: In Search of a Medication To Treat Methamphetamine Addiction, Part 2

April 2016
When lobeline turned out not to be the answer, it became a starting point. Dr. Linda Dwoskin and her team set out to transform the molecule into something more effective and with fewer side effects.

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Neuropeptide Promotes Behaviors Tied to Addiction and Overeating

July 2011
Reports on several studies implicating a certain neuropeptide (a signaling molecule) in fostering addition and overeating and discusses implications for addiction treatment.

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New Approach Uses Immune Cells To Deliver Anti-HIV Medications

October 2014
Nano-antiretroviral therapy (nano-ART) turns macrophages—one of the very cell types that HIV uses to replicate and spread through the body—into carriers for anti-HIV medications. The approach has the potential to make treatment for HIV easier and more effective.

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New Class of Regulators for Addiction Genes

November 2011
New studies show that microRNAs, snippets of RNA implicated in a wide variety of biological processes, are involved in promoting and inhibiting cocaine addiction. The findings could pave a new path for the development of anti-addiction therapies.

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New Therapy Reduces Drug Abuse Among Patients With Severe Mental Illness

June 2008
Describes a new intervention that enhances recovery prospects for substance abusers whose mental illness complicates the path toward recovery.

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