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NIDA Notes Articles: Treatment Research

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A Rapid Teen Substance Use Screening Tool for Clinicians

July 2015
Answers to three simple questions can help a busy health care provider flag a teen’s problematic use of alcohol, tobacco, or marijuana.

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Brief Intervention Helps Adolescents Curb Substance Use

January 2013
NIDA-funded researchers have gathered evidence that brief interventions can help adolescents move away from drug use. In a clinical trial, middle and high school students markedly reduced their substance use following two 60-minute sessions that combined motivational interviewing and cognitive behavioral therapy.

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Buprenorphine Benefits Waitlisted Seekers of Opioid Treatment

March 2017
In two pilot clinical trials, buprenorphine helped participants reduce their illicit opioid use and injection drug use while awaiting admission to a methadone or buprenorphine treatment program. Researchers minimized the risks for improper use or diversion of the study medication by giving it to trial participants in a computerized, tamper-proof device that dispenses one dose each day.

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California Reaped Large Savings by Diverting Drug-Using Offenders Into Treatment

February 2014
California’s Proposition 36, which allows qualified drug offenders to enter substance use treatment rather than go to jail or prison, saved the state close to $100 million in its first year.

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Cigarette Smoking Increases the Likelihood of Drug Use Relapse

May 2018
Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

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Digital Addiction Therapies Affirm Promise in Replication and Large Trial

November 2015
Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.

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Dr. Joni Rutter Q&A: How Basic Science Is Tackling Addiction

May 2014
One of NIDA’s goals is to try to understand the individual differences that contribute to whether or not someone who takes a drug will become addicted to it. Dr. Rutter’s research focuses on three types of differences: Environmental, developmental, and genetic and epigenetic.

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Dr. Kevin M. Gray Q & A: A Potential Medication for Marijuana Dependence

October 2014
Dr. Kevin M. Gray discusses why it’s the perfect time for discovering new evidence-based treatments for marijuana dependence. In an accompanying podcast, he discusses a clinical trial that examines NAC’s potential as a treatment for marijuana dependence among adults.

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Dr. Thomas Kosten Q & A: Vaccines To Treat Addiction

June 2015
In this article and accompanying podcast, Dr. Thomas Kosten discusses the idea and current status of antidrug vaccines to treat substance use and addiction.

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Dual Regimen Aims To Shorten Medication-Assisted Therapy

May 2016
Treatment that combines use of Bp/Nx and memantine may enable young adults addicted to opioids establish lasting abstinence after a relatively brief course of medication-assisted therapy, a pilot trial suggests.

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